Flashcards in Zoonotic and vector borne infections Deck (17):
What are the flaviviruses?
West Nile, Dengue, Yellow Fever, St. Louis Encephalitis
What percentage of people with WNV infection develop West Nile Fever?
How is SLE transmitted?
Culex mosquitoes acquire disease from infected birds
What are the symptoms of severe SLE infection?
Headache, high fever, stiff neck, stupor, disorientation, coma, tremors, occasional convulsions, spastic paralysis
What are the togaviruses?
1. Eastern equine encephalitis (EEE) 2. Western equine encephalitis (WEC) 3. Venezuelan equine encephalitis (VEE)
What makes VEE different from EEE and WEE?
Most cases ARE symptomatic
What is the transmission for hantavirus?
Inhalation of dried feces and urine from infected rodents
What is the unique feature of LaCrosse encephalitis?
Maintained in natural life cycle in chipmunks and rodents
How is LaCrosse encephalitis transmitted?
LaCrosse encephalitis is mainly seen in what age group?
What is the pathogenesis of rabies?
Virus proliferates locally, then heads to CNS - incubation of days to months then disseminates to peripheral nerves
What is the treatment for rabies?
Post-exposure prophylaxis - 1 does Ig and 5 doses vaccine over a 28 day period
What type of virus is lymphocytic choriomeningitis virus (LCMV)?
What are the symptoms of lymphocytic choriomeningitis virus (LCMV)?
1. Rodent borne virus - causes aseptic meningitis, encephalitis, meningoencephalitis 2. Biphasic pattern of illness
How is LCMV spread?
Common house mouse - inhalation of infectious aerosolized particles of rodent urine, feces, saliva
How are PrPc and PrPsc different?
PrPc has numerous alpha helices, PrPsc has beta pleated sheets