Flashcards in Viral infections of skin and soft tissue II Deck (40)
What type of lesion spread is seen in smallpox?
Centrifugal - mostly on face and extremities
What are the features of the smallpox lesion?
Pustular / scabbing, firm to the touch
What family does variola virus belong to?
What is the variola virus genome?
Where does variola virus replicate?
What virus is responsible for smallpox?
What comprises the smallpox vaccine?
Live strain of a vaccinia virus (different poxviridae family member)
How can smallpox be differentiated from chickenpox?
Smallpox lesions develop on hands and feet and are synchronous
What are the 3 Cs associated with measles?
Cough, coryza, conjunctivitis
What sign is pathognomonic for measles?
Koplik's spots - small white spots with red borders opposite molars on oral mucosa
How is the measles rash described?
Maculopapular, beginning at the hairline and spready downward
What family does the measles virus belong to?
What is the measles virus genome?
Is the measles virus enveloped or non-enveloped?
Which gene is important for fusion of measles virus?
Which protein is important for attachment of measles virus?
What percentage of measles cases involve complications?
What type of vaccine is the measles vaccine?
When is the measles vaccine recommended?
12-15 months, then at 4-6 years
How is the German measles rash described?
Maculopapular, appearing first on face then spreading downward - does not coalesce
Which virus is responsible for German measles?
What are the symptoms of congenital rubella syndrome?
Deafness, cataracts, congenital glaucoma, congenital heart disease, pigmentary retinopathy, purpura, hepatosplenomegaly
What family does the rubella virus belong to?
Is the rubella virus enveloped or non-enveloped?
What is the rubella virus genome?
What type of vaccine is the rubella vaccine?
What are the symptoms of fifth disease / erythema infectiosum?
Fever, characteristic rash beginning on cheeks
What virus is responsible for fifth disease?
What is the fifth disease genome?