W3-5 Inhibitors of Cell Wall Synthesis Flashcards Preview

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Flashcards in W3-5 Inhibitors of Cell Wall Synthesis Deck (14)
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1

Daptomycin

depolarizes cell membrane (non-β-lactam)

2

Polymyxin B

poly-aggregates create membrane holes, spill contents spill out of cell (non-β-lactam)

3

Bacitracin

prevents dephosphorylation events that are used to build cell wall (non-β-lactam)

4

Vancomycin

transglycocelation (non-β-lactam)

5

Carbapenems

imipenem, meropenem
transpeptidase inhibitor (β-lactam)

6

Benzathine

IM penicillin injection

7

Probenecid

penicillin additive, slows excretion of weak acids

8

Naficillin and Dicloxicillin
Antistaphylococcal penicillins

penicillinase-resistant

9

Binds irreversibly to penicillinase

Clavulanate

10

Beta-lactamase inhibitors

Sulbactam and Tazobactam

11

Aminopenicillinases

Ampicillin and Amoxicillin
can pass through porin channels, also Gram (-)

12

Antipseudomonals

Ticarcillin and Piperacillin

13

Antiallergenic penicillin

Aztreonam
only Gram (-)

14

Cephalosporins

cef