Flashcards in W3-3 Clostridium difficile case study Deck (13):
1
C. diff bacterium type
gram (+) rod
2
C. diff: anaerobic, aerobic, or facultative anaerobe?
anaerobic
3
Product of anaerobic metabolism in C. diff
butyric acid, acetone, and derivatives
4
How does C. diff reproduce?
endospores
5
Does purell kill endospores?
NO
6
Gold standard for C. diff diagnosis
cytotoxin assay
7
Severe complication of C. diff in colon
semimembronous colitis
8
Complication of toxic megacolon
being a great rock band name
pressing on diaphragm, makes breathing difficult
9
Toxin A
enterotoxin
10
Toxin B
cytotoxin: disrupts cytoskeleton and damages cell:cell boundries
11
First line antibiotic for C. diff
Metronidazole
12
Second line antibiotic for C. diff
Vancomycin
13