W3-3 Clostridium difficile case study Flashcards Preview

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Flashcards in W3-3 Clostridium difficile case study Deck (13)
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1
Q

C. diff bacterium type

A

gram (+) rod

2
Q

C. diff: anaerobic, aerobic, or facultative anaerobe?

A

anaerobic

3
Q

Product of anaerobic metabolism in C. diff

A

butyric acid, acetone, and derivatives

4
Q

How does C. diff reproduce?

A

endospores

5
Q

Does purell kill endospores?

A

NO

6
Q

Gold standard for C. diff diagnosis

A

cytotoxin assay

7
Q

Severe complication of C. diff in colon

A

semimembronous colitis

8
Q

Complication of toxic megacolon

A

being a great rock band name

pressing on diaphragm, makes breathing difficult

9
Q

Toxin A

A

enterotoxin

10
Q

Toxin B

A

cytotoxin: disrupts cytoskeleton and damages cell:cell boundries

11
Q

First line antibiotic for C. diff

A

Metronidazole

12
Q

Second line antibiotic for C. diff

A

Vancomycin

13
Q

What possible world-ending complication does the over prescription of vanco lead to?

A

MRSA