W3-3 Clostridium difficile case study Flashcards Preview

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Flashcards in W3-3 Clostridium difficile case study Deck (13):
1

C. diff bacterium type

gram (+) rod

2

C. diff: anaerobic, aerobic, or facultative anaerobe?

anaerobic

3

Product of anaerobic metabolism in C. diff

butyric acid, acetone, and derivatives

4

How does C. diff reproduce?

endospores

5

Does purell kill endospores?

NO

6

Gold standard for C. diff diagnosis

cytotoxin assay

7

Severe complication of C. diff in colon

semimembronous colitis

8

Complication of toxic megacolon

being a great rock band name
pressing on diaphragm, makes breathing difficult

9

Toxin A

enterotoxin

10

Toxin B

cytotoxin: disrupts cytoskeleton and damages cell:cell boundries

11

First line antibiotic for C. diff

Metronidazole

12

Second line antibiotic for C. diff

Vancomycin

13

What possible world-ending complication does the over prescription of vanco lead to?

MRSA