Nucleic Acids Flashcards Preview

Foundations > Nucleic Acids > Flashcards

Flashcards in Nucleic Acids Deck (26):
1

Purines

Adenine, Guanine

2

Pyrimidines

Thyamine, Cytesine, Uracil

3

# of hydrogen bonds AT or AU

2

4

# of hydrogen bonds GC

3

5

Positively charged protein balls holding DNA together

Histones

6

Histones + DNA = ??

Nucleosome

7

What is a nucleoside missing vs a nucleotide?

Phosphates

8

Which DNA conformation is most common?

B-DNA

9

What does a FISH stain do?

Labels each chromosome a different color

10

T/F Total # of chromosomes directly corresponds to species complexity

F

11

T/F Level of gene regulation directly corresponds to species complexity

T

12

What are the functions of introns?

Possibly gene regulation through microRNAs or may influence promotor binding

13

Amount of condensation in DNA of eukaryotes

10,000x

14

Histones contain large amounts of which amino acids?

Arginine and Lysine

15

What is the function of the H1 protein?

Link DNA between histones

16

How are histone tails modified for the regulation of gene expression most commonly?

Acetylation of lysine residues (acetylation = gene expression)

17

"Loose" chromatin

Euchromatin

18

Condensed chromatin

Heterochromatin

19

This enzyme is often unregulated in cancerous cells, silencing tumor suppression genes and may be a target for drugs

HDACs (histone deacetylase)

20

At which carbon is deoxyribose missing an alcohol?

2 prime

21

In what order is mRNA processed?

1. 5' cap
2. 3' poly-A tail
3. Splicing

22

Prokaryotic rRNA subunits

5S, 23S, 16S

23

Eukaryotic rRNA subunits

5S, 5.8S, 18S, and 28S

24

Which end of the tRNA is complementary to the condon for an amino acid?

5'

25

Which end of the tRNA contains the amino acid?

3'

26

How many bp do micro-RNAs usually consist of?

21-22