Week 4 Flashcards
energy Storage
stored in chemical bonds and released and transformed by metabolic pathways
Free Energy
available to do work
Metabolic Principle 1
chemical transformations occur in series of intermediate reactions that form a metabolic pathway
Metabolic Principle 2
Each reaction is catalysed by a specific enzyme
Metabolic Principle 3
Most Metabolic pathways are similar and are controlled by enzymes that are inhibited or actived
Metabolic Principle 4
In eukaryotes metabolic pathways occur inside organelles
Endergonic
energy requiring
Exergonic
energy releasing
Hydrolysis of ATP
exergonic
produces ADP and free energy
Reduction
gain of electrons
Oxidation
loss electrons
The more reduced a molecule
more energy in bond
NAD+
oxidizing form
NADH
reducing form
Catabolic Reactions
usually release energy that is used to drive chemical reactions
Anabolism
chemcial reactions which substances are combined to form complex molecules
requires energy
build new molecules and store energy
Cellular Respiration
metabolic reactions used to harvest energy
energy is released when reduced molecules with many c & H bonds are fully oxidised into CO2
Glycolysis
takes place in cytosol
- final products are 2 pyruvite, 2 ATP and 2 NADH
Pyruvate Oxidation
occurs in mitochondria
produces CO2 and acetate, acetate is then bonded to CoEnzymeA to form acetyl CoA
NAD+ goes to NADH
Citric Acid Cycle
occurs in mitochondria
operates for every 2 molecules of glucose
starts with acetyl CoA, acetyl is oxidised into 2 CO2
Oxidative Phosphorylation
NADH oxidation is used to actively transport H+ across inner membrane
diffusion of H+ back across drives synthesis of ATP
Electron Transport
electrons from oxidation of NADH and FADH2 pass from one carrier to the next chain
exergonic
transports H+ across membrane
ATP Synthase
uses H+ gradient to drive ATP synthesis by chemiosmosis
converts potential energy of H+ gradient into chemical energy
Chemiosmosis
movement of ions across semi permeable barrier from region of high to low