Week 9 Flashcards
(105 cards)
Endocrine cells
secretes hormones into blood
Nerve and endocrine cells - interaction
work together to ensure proper functioning of body system
Nerve and endocrine cells - communication
most intercellular communication takes place by chemical signals that travel to another cell
Target cell
cell that signal molecules bind to in order to trigger response
Nerve control
fast and quick
impulses are delivered to highly defined target cells
Endocrine control
slow and last a long time in the blood, can alter gene transcription
broadcast to all cells potentially
Nervous system functions
controls movement of skeletal muscles
Endocrine system function
controls prolonged activities
Paracrines
chemicals secreted by one cell that affects neighbouring cells
Autocrines
chemicals that are secreted into intercellular fluids that diffuse to receptors on very same cell
Hormones
carried throughout the body by blood circulation
Neurotransmitters
move across the synaptic cleft, secretion may be controlled by impulses that originated far from release site
Pheromones
released into environment and affect other individuals
Exocrine glands
secrete substances into a duct or body cavity
Endocrine cells
secrete substances into blood
Hormone
chemical substance, secreted into blood by endocrine cells that regulate the function of other cells
act at very low blood concentrations
Neurosecretory cells
resemble neurons
propagate action potentials
cell bodies are in CNS
direct interface between nervous and endocrine system
Nonneural endocrine cells
stimulated to secrete hormones by other hormones
Peptide and protein hormones
water soluble and easily transported in blood
packages in vesicles and released to blood by exocytosis
cant cross cell membrane
Steriod hormones
synthesised from cholestrol lipid soluble, bound to carrier proteins in blood
Amine hormones
modified amino acids
may be lipid soluble or water soluble `
Hormone binding - on target cell surface
binds to part of the receptor protein outside membrane
many receptors are G protein linked
G protein linked receptors
initiate second messenger signaling cascades inside target cell
Hormone binding - inside target cell
lipid soluble hormones can diffuse through cell membrane