Week 5 Flashcards

(46 cards)

1
Q

Cell division - importance

A

in growth and repair of multicellular organisms

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2
Q

Asexual reproduction

A

offsprings are clones
genetically identical to parents
any genetic variation is due to mutations

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3
Q

single celled prokaryotes - reproduction

A

binary fission

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4
Q

Single celled eukaryotes - reproduction

A

mitosis and cytokinesis

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5
Q

mulitcellular eukaryotes - reproduction

A

reproduce by asexual

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6
Q

Sexual reproduction

A

involves fusion of gametes
results in genetic variation
gametes formed by meiosis

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7
Q

somatic cells

A

body cells

contains 2 sets of chromosomes that occur in homologous pairs

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8
Q

Gametes

A

sex cells

one pair of chromosomes

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9
Q

fertilisation

A

2 haploid cells form a zygote

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10
Q

Sexual reproduction - essence

A

random selection

fusion of haploid gametes to make dipliod cell

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11
Q

Four events of cell division

A

reproductive signals
DNA replication
DNA segregation
Cytokinesis

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12
Q

Replication

A

ocurs as the DNA is threaded through a replication complex of proteins at center of the cell

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13
Q

Segregation

A

as replication proceeds, the ori complexes move to opposite ends of the cell
DNA spequences adjacent to ori region bind to proteins for segregation using ATP
Actin protien provide filaments along which ori and other proteins move

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14
Q

ori

A

where replication starts

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15
Q

ter

A

where replication ends

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16
Q

important regions of circular chromosome

A

ter

ori

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17
Q

cytokinesis

A

after chromosome segregation, cell membrane pinches in and new cell walll is made

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18
Q

Mitosis

A

one nucleus produces 2 daugther nuclei containing same number of chromosomes
continuous

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19
Q

M phase: mitosis

A

segragation of chromosomes into 2 nuclei, followed by cytokinesis

20
Q

Interphase: Mitosis

A

cell nucleus is visible and cell functions occur, including DNA replication

21
Q

Interphase mitosis subphases

A

G1 - variable
S pahse - DNA is replicated
G2- cell prepares for mitosis , synthesises microtubules for segregating chromosomes

22
Q

Prophase

A

3 structures appear
condensed chromosomes
reoriented chromosomes
spindle

23
Q

Karotype

A

the condensed chromosomes distinguished by their sizes and centromere positions

24
Q

centrosome

A

determines orientation of spindle
consists of 2 centrioles
poles at which the chromosomes move twards

25
centrioles
hollow tubes formed by microtubules
26
spindle
made up of polar microtubules astral microtubules Kinetochore microtubules
27
polar microtubules
overlap in middle region of cell and keep poles apart
28
Astral microtubules
interact with proteins attached to cell membrane, keeps poles apart
29
Kinetochore microtubules
attach to kinetochores on chromatid centromeres
30
Prometaphase: mitosis
nuclear envelope breaks down and chromatids attach to kinetochore microtubules
31
Metaphase: mitosis
the chromosomes line up at midline of cell
32
Anaphase: mitosis
chromatids separate and daughter chromosomes move towards poles
33
Telophase: mitosis
nuclear envelopes form around each set of chromosomes and nucleoli appear, and spindle breaks down and chromosomes become less compact
34
Cytokinesis: mitosis
in animal cells, cell membrane pinches in between nuclei | in plant cells, vesicles appear along plane of cell division and fuse to form new cell membrane
35
Cyclin dependent kinases
trigger substances catalyse phosphorylation of proteins that regulate cell cylce and are activated by binding to cyclin, which exposes the active site
36
Meiosis
two nuclear division reduces chromosome number to haploi generates diversity
37
Meiosis 1
chromosomes come together and line up along lengths | pairs seperate but individual chromosomes made up of 2 chromatids remain together
38
Meiosis 2
not preceded by DNA replication sister chromatids seperate 4 haploid cells are produced
39
crossing over
prophase 1 - chromosomes repel each other but remain attached at chiasmata genetic material is exchanged between non sister chromosomes increases genetic variation
40
Independent assortment
at anaphase 1, matter of chance which member of homologous pair goes to which daughter cell
41
Nondisjunction
homologous pairs fail to separate at anaphase 1 | sister chromatids fail to separate at anaphase 2
42
aneuploidy
abnormal numbers of chromosomes
43
polyploidy
organisms with triploid, tetraploid or higher can form | can occur through extra round of DNA replication or lack of spindle formation
44
Translocation
crossing over between non homologous chromosomes
45
necrosis
cell is damaged or starved for oxygen or nutrients | cells swell and burst
46
Apoptosis
genetically programmed cell death