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Flashcards in 00 Antidotes Deck (29):
1

What is the poison centers phone number?

800-222-1222

2

When should Syrup of Ipecac be given?

Use if ingestion occurred w/in 60 minutes. Obtain only with advise from poison control center (that means you should call them first)

3

When is Syrup of Ipecac contraindicated?

< 6 months old. Pt with CNS depression or seizure. Ingestion from strong acid, alkali or sharp object. Ingestion of petroleum distillate. Pt with compromised airway. Pt already vomiting post ingestion. Ingestion of agent with fast onset of action

4

What ingredients are found in Activated Charcoal?

Actidose and Sorbitol

5

When is Activated Charcoal most effective?

When poison ingested < 1 hour. Absorbs almost all drugs and chemicals, must mix powder with 8 oz of water

6

What types of medications/substances does Activated Charcoal not work again?

Most heavy metals, Lithium, Methanol, Arsenic, Cyanide, Strong acids or alkalis

7

What is Ofirmev?

Brand name of IV APAP

8

What is the PO antidote for APAP overdose?

N-acetylcysteine (Mucomyst)

9

What is the IV antidote for APAP overdose?

Acetadote

10

How is Mucomyst (N-acetylcysteine) dosed?

140mg/kg LD then 70mg/kg Q4h x17 doses (18 total doses)

11

How is Acetadote dosed?

150mg/kg infused over 60 min, then 50mg/kg infused over 4 hours, then 100mg/kg infused over 16 hours

12

What is the antidote for Anticholinergic overdose?

Phyostigmine salicylate (Antilirium)

13

What is the antidote for Benzodiazepine overdose?

Flumazenil (Romazicon)

14

How is Romazicon (Flumazenil) dosed?

0.3mg IV over 30 sec. Repeat 0.5mg over 30 sec at 1 min intervals if needed (Max cumulative dose: 5mg)

15

What is the antidote for CCB overdose?

Calcium salts or Glucagon. Lipid emulsion therapy

16

What is the antidote for Beta-Blocker overdose?

Glucagon. Lipid emulsion therapy

17

What is the antidote for Digoxin overdose?

Digibind, DigiFab

18

What is the antidote for Heparin overdose?

Protamine

19

How is Protamine dosed?

1mg protamine neutralizes 100 units of heparin (max dose = 50mg) dosed based on known amount ingested and time since ingestion occurred

20

What is the antidote for Warfarin overdose?

Vitamin K (Mephyton). FFP (fresh frozen plasma)

21

What is the antidote for Iron overdose?

Deferoxamine (Desferal)

22

What is the antidote for Lead/Iron?

Succimer (Chemet)

23

What is the antidote for Lead?

Dimercaprol (BAL in oil) - contains peanut oil

24

What is the antidote for Methemoglobinemia?

Methylene blue

25

What is the antidote for TCA overdose?

Sodium bicarbonate (1-2 mEq/kg (1 amp = 50 mEq))

26

What is the antidote for Organophosphates (pesticides, chemical warfare) ingestion?

Atropine + Pralidoxime (Duodote) (Protopam 2-PAM)

27

What is the antidote for Opioid overdose?

Naloxone (Narcan)

28

How is Narcan (Naloxone) dosed?

0.2-0.4mg Q2-5min, give IM, IV, or SQ

29

What is Evzio?

(Naloxone): first FDA approved auto-injector