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Flashcards in 00 Hypertension Deck (103)
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1

What blood pressure is considered "Pre-Hypertension"?

S: 120-139 or D: 80-89

2

What blood pressure is considered "Stage 1 Hypertension"?

S: 140-159 or 90-99

3

For the general population > 60 years, when should BP treatment be initiated?

SBP: 150+ or DBP: 90+

4

For the general population < 60 years, when should BP treatment be initiated?

SBP: 140+ or DBP: 90+

5

For 18+ years with CKD, when should BP treatment be initiated?

SBP: 140+ or DBP: 90+

6

For 18+ years with diabetes, when should BP treatment be initiated?

SBP: 140+ or DBP: 90+

7

What is recommended for initial treatment in the general population +/- DM (non-black)?

Thiazide diuretic, CCB, ACE-I, ARB

8

What is recommended for initial treatment in 18+ years, CKD, any race, +/- DM?

ACE-I or ARB (both of these could be initial or add-on to improve kidney outcomes)

9

What is recommended for initial treatment in the general black population?

Thiazide diuretic, CCB

10

If a loop and thiazide are given together, how must you space them?

Thiazide first, followed by loop one hour later

11

How do thiazides work?

Inhibits sodium reabsorption in the DISTAL CONVOLUTED TUBULES --> increase water excretion

12

What is the generic name for Diuril?

Chlorothiazide (Thiazide)

13

What is the generic name for Lozol?

Indapamide (Thiaizde)

14

What is the generic name for Zaroxolyn?

Metolazone (Thiaizde)

15

What is the generic name for Thalitone?

Chlorthalidone (Thiazide)

16

What is the only thiazide that can be given IV?

Diuril (Chlorothiazide)

17

What are the only thiazides that are effective when CrCl < 30?

Lozol (Indapamide) and Zaroxolyn (Metolazone)

18

What are the electrolyte imbalances caused by thiazides?

Hypo: K, Na, Mg, Cl. Hyper: Ca

19

What are the metabolic ADRs caused by thiazides?

Hyperglycemia, hyperuricemia, hypercholesterolemia. Photosensitivity

20

What are the contraindicates to thiazide use?

Sulfa allergy, Anuria, Renal decomposition, Pregnancy

21

What is the MOA of loop diuretics?

Inhibits Na and Cl reabsorption in the ASCENDING LOOP OF HENLE and the distal renal tubule --> increased water excretion

22

What is the generic name of Lasix?

Furosemide (loop)

23

What is the generic name of Demadex?

Torsemide (loop)

24

What is the generic name of Bumex?

Bumetanide (loop)

25

What is the generic name of Edecrin?

Ethacrynic Acid (loop) - only loop and thiazide that has no precaution with sulfa allergy

26

What are the Oral Loop Equivalents?

40 furosemide ~ 1 bumetanide ~ 10-20 torsemide

27

Whats unique about the IV formulations of loop diuretics?

They are light sensitive

28

What are the electrolyte imbalances caused by Loops?

Hypo: Na, K, Mg, Cl, AND Ca

29

When are Loops contraindicated?

Anuria

30

What is the BBW with Loops?

Excessive amounts --> profound diuresis --? fluid/electrolyte depletion