00 Chronic Obstructive Pulmonary Disease (COPD) Flashcards Preview

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Flashcards in 00 Chronic Obstructive Pulmonary Disease (COPD) Deck (11):
1

What is the definition of Chronic Bronchitis?

Inflammatory response in the larger airways which consists of CHRONIC COUGH AND SPUTUM PRODUCTION for most days out of 3 months in at least 2 consecutive years

2

What are the symptoms of Chronic Bronchitis?

Productive cough. "Blue bloaters". Usually overweight

3

What is the definition of Emphysema?

IRREVERSIBLE ENLARGEMENT OF AIRSPACES distal to terminal bronchioles, ALVEOLAR WALL DESTRUCTION, airflow obstruction. Reduction of surface area for gas exchange

4

What are the symptoms of Emphysema?

Minimal cough. "Pink puffers". Usually thin. Dyspnea, even at rest

5

Which vaccines are recommended for patients with COPD?

Influenza vaccine annually. Pneumococcal vaccine (CDC recommends for < 65 with chronic lung disease (COPD, emphysema, asthma) and all patients 65+

6

What are the two main pharmacologic choices for COPD?

Bronchodilator (SABA/LABA, anticholinergics, theophylline, combination of these drugs). Steroids

7

What is the recommended treatment for Stage I: Mild COPD?

SABA or SAMA prn

8

What is the recommended treatment for Stage II Moderate COPD?

LABA or LAMA

9

What is the recommended treatment for Stage III Severe COPD?

ICA + LABA or LAMA

10

What is the recommended treatment for Stage IV Very Severe COPD?

ICS + LABA and/or LAMA + Long-term oxygen therapy if chronic respiratory failure, consider surgical procedure

11

What is the generic name of Daliresp?

Roflumilast (PDE-4 Inhibitor) - reduces inflammation by inhibiting breakdown of intracellular cyclic AMP and cGMP