00 Male Issues

Question 1

What is the normal range for Prostate Specific Antigen (PSA)?

Answer 1

0-4 ng/mL

Question 2

What are some medications that may worsen BPH?

Answer 2

Anticholinergics (TCAs, antipsychotics, etc), Antihistamines, Decongestants, Diuretics, Caffeine

Question 3

What is the generic name of Hytrin?

Answer 3

Terazosin - BPH (Non-selective Alpha-1 blocker)

Question 4

What is the generic name of Cardura?

Answer 4

Doxazosin - BPH (Non-selective Alpha-1 blocker)

Question 5

What is the generic name of Uroxatral?

Answer 5

Alfuzosin - BPH (Non-selective Alpha-1 blocker)

Question 6

What is the generic name of Flomax, Jalyn?

Answer 6

Tamsulosin - BPH (Selective Alpha-1a blocker)

Question 7

What is the generic name of Rapaflo?

Answer 7

Silodosin - BPH (Selective Alpha-1a blocker)

Question 8

What is important to know about Alpha-1 blockers in BPH?

Answer 8

1st dose phenomenon (orthostatic hypotension), dose at night. Does NOT affect PSA levels nor shrink the prostate. Can cause Priapism

Question 9

What is important to know about 5-alpha reductase inhibitors in BPH?

Answer 9

Associated with prostate SHRINKAGE and symptom improvement. Delayed onset of response vs alpha blockers

Question 10

What is the generic name of Proscar?

Answer 10

Finasteride - BPH (5-alpha reductase inhibitor)

Question 11

What is the generic name of Avodart, Jalyn?

Answer 11

Dutasteride - BPH (5-alpha reductase inhibitor)

Question 12

What pregnancy category are the 5-alpha reductase inhibitors used for BPH?

Answer 12

Category X

Question 13

What are the main ADRs for 5-alpha reductase inhibitors for BPH?

Answer 13

Sexual dysfunction, Breast swelling and tenderness

Question 14

What is the generic name of Viagra?

Answer 14

Sildenafil (PDE-5 inhibitor)

Question 15

What is the generic name of Cialis?

Answer 15

Tadalafil (PDE-5 inhibitor)

Question 16

What is the generic name of Levitra?

Answer 16

Verdenafil (PDE-5 inhibitor)

Question 17

What is the generic name of Stendra?

Answer 17

Avanafil (PDE-5 inhibitor)

Question 18

When are PDE-5 inhibitors contraindicated?

Answer 18

With Nitrates!

Question 19

What are some unusual ADRs with PDE-5 inhibitors?

Answer 19

Transient abnormal blue/green vision (mostly with Sildenafil). Sudden vision loss d/t nonarteritic ischemic optic neuropathy (NAION). Priapism

Question 20

What is the generic name of Rogaine?

Answer 20

Minoxidil (used for baldness) - increases blood flow to hair

Question 21

What is the generic name of Propecia?

Answer 21

Finasteride (used for baldness) - inhibits testosterone –> DHT

Question 22

Which baldness medication can be used in both men and women?

Answer 22

Rogaine (Minoxidil)

Question 23

What are some medications that can induce hypogonadism?

Answer 23

Ketoconazole, Glucocorticoids, Spironolactone, Cimetidine, Phenytoin, Opioids, Alcohol, Anabolic steroids, Flutamide

Question 24

What type of allergy should Androgel, Striant, Testim be avoided in?

Answer 24

Soy

Question 25

What are the two oral medications that can be used for hypogonadism?

Answer 25

Methyltestosterone or Fluoxymesterone

Question 26

What are the oral preparations limitations for hypogonadism?

Answer 26

Poor oral bioavailability, Poor androgen effect, Adverse lipid changes, Priapism, Increased risk of hepatic side effects

Question 27

What is the generic name of Striant?

Answer 27

Testosterone buccal preparation - used for hypogonadism

Question 28

What are the advantages of testosterone buccal preparation (Striant)?

Answer 28

BID dosing allows for normal testosterone levels throughout the day

Question 29

What is the generic name of Androderm?

Answer 29

Testosterone transdermal patch (for hypogonadism). Should be applied in the evening, if it falls off you may press back on or replace before noon

Question 30

Where can Androderm patch be placed?

Answer 30

Upper arms or back. Abdomen. Thighs

Question 31

What are the advantages of using Androderm?

Answer 31

Closely mimics normal diurnal changes in testosterone levels

Question 32

What is the generic name of AndroGel?

Answer 32

Testosterone gel formulation

Question 33

What is the generic name of Testim?

Answer 33

Testosterone gel formulation

Question 34

Where can AndroGel be applied?

Answer 34

Upper arms or Abdomen

Question 35

Where can Testim be applied?

Answer 35

Upper arms only

Question 36

What is the generic name of Fortesta?

Answer 36

Testosterone gel formulation

Question 37

Where can Fortesta be applied?

Answer 37

To the thighs only!

Question 38

What is the generic name of Axiron?

Answer 38

Testosterone topical formulation used in armpit, apply deodorant first

Question 39

What should a patient do to minimize first-dose syncope with terazosin?

Answer 39

Start with 1mg daily