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MED 103- BIOLOGY I > 50. CANCER CELLS > Flashcards

50. CANCER CELLS Flashcards

1
Q
  1. Do cancer cells exhibit Density-Dependent Inhibition or Anchorage Dependence?
A
  • no
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2
Q
  1. What leads to a clump of overlapping cancer cells forming?
A
  • cancer cells continue to divide well beyond a single layer
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3
Q
  1. What is Transformation?
A
  • the process by which a normal cell becomes a cancer cell
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4
Q
  1. What are three ways in which Cancer cells do not normally respond to the body’s control mechanisms?
A
  • they make their own growth factors
  • they have a signalling pathways always ON
  • they have abnormal cell cycle control
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5
Q
  1. What two kinds of tumours do Cancer Cells form?
A
  1. BENIGN TUMOURS:
    • not invasive
    • contained at a particular site
  2. MALIGNANT TUMOURS:
    • invasive
    • they can spread to other organs
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6
Q
  1. What are Malignant Tumours?
A
  • they invade surrounding tissues
  • they export cells to other parts of the body
  • they may form secondary tumours
  • this is known as Metastasising
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7
Q
  1. What are 6 characteristics of Cancer Cells?
A
  1. They resist Cell Death
  2. They sustain Proliferative Signalling
  3. They evade Growth Suppressors
  4. They activate invasion and metastasis
  5. They enable replicative immortality
  6. They induce angiogenesis

ANGIOGENESIS:
- the formation of new blood vessels

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8
Q
  1. What causes Cancer Cells?
A
  • cancer is caused by an accumulation of multiple
    mutations
  • a heterogeneity of tumours
  • diverse physiological pathways and tissue
    specificity
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9
Q
  1. What is Precision Oncology?
A
  • this is the science of using a patient’s genetics to
    create a treatment plan
  • this plan is targeted to the molecular
    characteristics of their cancer
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10
Q
  1. Read through Summary 1.
    Does everything make sense?
A
  • yes
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11
Q
  1. Read through Summary 2.
    Does everything make sense?
A
  • yes
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12
Q
  1. Read through Summary 3.
    Does everything make sense?
A
  • yes
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13
Q
  1. Read through Summary 4.
    Does everything make sense?
A
  • yes
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14
Q
  1. Read through Summary 5.
    Does everything make sense?
A
  • yes
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15
Q
  1. Read through Summary 6.
    Does everything make sense?
A
  • yes
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16
Q
  1. Answer the following question.
A

D.

17
Q
  1. Answer the following Question.
A

A.

MED 103- BIOLOGY I (53 decks)

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