III - A. Virology | 15. Paramyxoviruses (RSV, Paramyxoviruses) Flashcards
I. Basics
1. What are the viruses belong to PARAMYXOVIRUSES group?
Name: „Para”= next to; „myxo”= mucus – mucosal infections
I. Basics
2. What are the genetic material and morphology of
- Non-segmented (-)ssRNA genome
- Enveloped
II. Parainfluenza virus
1. How does Parainfluenza virus spread?
Spread: respiratory droplets
- Common infections, esp. in children
II. Parainfluenza virus
2a. What are the diseases caused by Parainfluenza virus?
II. Parainfluenza virus
2B. What are the features of Croup?
II. Parainfluenza virus
3. What is the diagnosis of Parainfluenza virus?
Clinical signs, X-ray: steeple sign
II. Parainfluenza virus
4. What is the treatment of Parainfluenza virus?
Tx: no treatment against the virus
(cold humid air / steroid inhalation or suppository (Rectodelt)
/ bronchodilatator inhalation (Ventolin) / oxigen therapy / intubation )
II. Parainfluenza virus
5. Do we have vaccine for Parainfluenza virus?
Vaccine not available, under trial
III. Respiratory syncytial virus - RSV
1. How does Respiratory syncytial virus - RSV spread?
- Spread: respiratory droplets
- Common infection, nosocomial spread also possible
- Usually spread in autumn, winter, among children and elderly
III. Respiratory syncytial virus - RSV
2. What are the clinical forms of Respiratory syncytial virus - RSV?
III. Respiratory syncytial virus - RSV
3. How do we diagnose RSV?
- Clinical
- RSV PCR or antigen testing from nasal sample if necessary
III. Respiratory syncytial virus - RSV
4. What is the treatment for RSV?
No treatment available against the virus (Bronchodilators, epinephrine, and corticosteroids)
III. Respiratory syncytial virus - RSV
5. What is the Prevention for RSV?
Palivizumab – monoclonal antibody for premature babies (mRNA vaccine in trial)
