Induction Meds: Opioids Agonist-Antagonist - Other drugs Flashcards
1
Q
Which two drugs have resistance to Naloxone?
A
- Buprenorphine and Bremazocine.
S13 and S14
2
Q
Opioid Agonist-Antagonist
What are drug facts of Nalorphine?
A
- equally potent with Morphine
- Not used clinically: high incidence of dysphoria (σ receptors)
S14
3
Q
Opioid Agonist-Antagonist
What are drug facts of Bremazocine?
A
- κ receptors 2x potent > Morphine
- Naloxone = not effective as reversal (could be other receptors)
S14
4
Q
Opioid Agonist-Antagonist
What are drug facts of Decozine?
A
- δ & µ: analgesia, no CV
- 0.15 mg/kg IM= Morphine
- 10 to 15 mg IM rapid absorption
- Onset: 15 mins.
S14
5
Q
What are drug facts of Meptazinol?
A
- mu1 receptors
-
100 mg = 8 mg Morphine
** Rapid onset - Duration: < 2 hrs
- Protein binding: 25%
S14