Induction Meds: Opioids Agonist-Antagonist - Other drugs Flashcards

1
Q

Which two drugs have resistance to Naloxone?

A
  • Buprenorphine and Bremazocine.

S13 and S14

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2
Q

Opioid Agonist-Antagonist

What are drug facts of Nalorphine?

A
  • equally potent with Morphine
  • Not used clinically: high incidence of dysphoria (σ receptors)

S14

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3
Q

Opioid Agonist-Antagonist

What are drug facts of Bremazocine?

A
  • κ receptors 2x potent > Morphine
  • Naloxone = not effective as reversal (could be other receptors)

S14

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4
Q

Opioid Agonist-Antagonist

What are drug facts of Decozine?

A
  • δ & µ: analgesia, no CV
  • 0.15 mg/kg IM= Morphine
  • 10 to 15 mg IM rapid absorption
  • Onset: 15 mins.

S14

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5
Q

What are drug facts of Meptazinol?

A
  • mu1 receptors
  • 100 mg = 8 mg Morphine
    ** Rapid onset
  • Duration: < 2 hrs
  • Protein binding: 25%

S14

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