Pharm Adjunct: Vasodilator - CCB: Nicardipine (Cardene) Flashcards
1
Q
What are the three categories of CCBs?
Where do each interact?
A
- AV Node (Phenylalkylamines & Benzothiazepines)
- Vasculature (Dihydropyridines)
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2
Q
How do CCBs generally work?
A
Bind and block VG-Ca⁺⁺ channels thus ↓ Ca⁺⁺ influx.
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3
Q
CCBs will ___ blood pressure and ___ coronary blood flow.
A
decrease; increase
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4
Q
Which CCB has the greatest coronary artery dilation and least myocardial depression?
A
Nicardipine
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5
Q
What is the dose of nicardipine?
A
5mg/hr (2.5mg titration)
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