Induction Meds: Opioids Agonist - Others Flashcards

1
Q

Which opioid is most cleared?

A

Remifentanil (3-4L/min)

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2
Q
A
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3
Q

Which opioid(s) is/are the most protein bound?
Which is the least?

A
  • most = Sufentanil, alfentanil, & remifentanil
  • least = morphine

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4
Q

Which opioid is the highest percent non-ionized?

A

Alfentanil

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5
Q

What are the other Opioid Agonists?

A
  • Oxymorphone
  • Oxycodone
  • Hydrocodone
  • Methadone
  • Propoxyphene
  • Tramadol
  • Heroin

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6
Q

Which Opioid Agonist is used in opioid withdrawal & chronic pain?

A

Methadone

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7
Q

What are the drug facts about Tramadol?

A
  • 5 -10x less (Morphine)
  • µ with weak κ & δ
  • PO: 3 mg/kg
  • Interacts with Coumadin

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8
Q

What are drug facts of Heroin?

A
  • More rapid onset
  • less N/V
  • great potential for dependency

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