Induction Meds: Opioids Antagonist - Methylnaltrexone and Alvimopan + Abuse Resistant Opidoids Flashcards by Krista Flores | Brainscape

Q

What is Methylnaltrexone’s use?

A

Anti-emetic (antagonizes N/V from opioids)
promotes gastric emptying

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Q

What is Alvimopan and what is it used for?

Why can’t it be used long term?

A

μ-selective PO peripheral opioid antagonist for post-op ileus.
CV problems long term

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Q

Where is Alvimpan metabolized?

A

gut flora

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Q

What are the abuse-resistant opioid formulations?

A

Suboxone (buprenorphine + naloxone)
Embeda (long-release morphine + naltrexone)
OxyNal (oxycodone + naltrexone)

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