Induction Meds: Opioids Antagonist - Methylnaltrexone and Alvimopan + Abuse Resistant Opidoids Flashcards
1
Q
What is Methylnaltrexone’s use?
A
- Anti-emetic (antagonizes N/V from opioids)
- promotes gastric emptying
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2
Q
What is Alvimopan and what is it used for?
Why can’t it be used long term?
A
- μ-selective PO peripheral opioid antagonist for post-op ileus.
- CV problems long term
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3
Q
Where is Alvimpan metabolized?
A
gut flora
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4
Q
What are the abuse-resistant opioid formulations?
A
- Suboxone (buprenorphine + naloxone)
- Embeda (long-release morphine + naltrexone)
- OxyNal (oxycodone + naltrexone)
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