Induction Meds: Opioids Antagonist - Methylnaltrexone and Alvimopan + Abuse Resistant Opidoids Flashcards

1
Q

What is Methylnaltrexone’s use?

A
  • Anti-emetic (antagonizes N/V from opioids)
  • promotes gastric emptying

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2
Q

What is Alvimopan and what is it used for?

Why can’t it be used long term?

A
  • μ-selective PO peripheral opioid antagonist for post-op ileus.
  • CV problems long term

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3
Q

Where is Alvimpan metabolized?

A

gut flora

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4
Q

What are the abuse-resistant opioid formulations?

A
  • Suboxone (buprenorphine + naloxone)
  • Embeda (long-release morphine + naltrexone)
  • OxyNal (oxycodone + naltrexone)

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