Multimodal: 5HT3 Ondansetron Flashcards

1
Q

Ondansetron is equivocal to what two drugs in its treatment of N/V?

A

Droperidol & Metoclopramide

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2
Q

What is the duration of Ondansetron?

A

plasma half life is 4 hours!

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3
Q

What is the MOA of Ondansetron and the use?

A
  • First 5-HT3 antagonist
  • Approved for CINV

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4
Q

What are the side effects of Ondansetron?

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A
  • HA
  • Constipation
  • some QT prolongation

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4
Q

What is the dose of Ondansetron?

A

4 mg IV (up to 8 mgs)

Pediatrics: 0.1 mg/kg IV

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