Pharm Adjunct: Vasodilator - CCB: Nicardipine (Cardene) Flashcards

1
Q

What are the three categories of CCBs?
Where do each interact?

A
  • AV Node (Phenylalkylamines & Benzothiazepines)
  • Vasculature (Dihydropyridines)

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2
Q

How do CCBs generally work?

A

Bind and block VG-Ca⁺⁺ channels thus ↓ Ca⁺⁺ influx.

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3
Q

CCBs will ___ blood pressure and ___ coronary blood flow.

A

decrease; increase

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4
Q

Which CCB has the greatest coronary artery dilation and least myocardial depression?

A

Nicardipine

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5
Q

What is the dose of nicardipine?

A

5mg/hr (2.5mg titration)

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