Sex Development 1 Flashcards
Differentiate chromosomal, gonadal and phenotypic sex.
1
Q
Chromosomal sex
A
- Chromosomal distribution after first and second meiotic division
-
XX = female
- Once copy inactivated as a Barr Body
- At least two copies of some of the genes are needed for normal ovarian differentiation
-
XY = male
- At least one copy of the X chromosome for males is necessary for normal testicular differentiation
2
Q
Gonadal sex
A
- Differentiation of gonads after the bipotential stage
- Ovary
- granulosa cells - follicle development
- Testis
- sertoli cells - Mullerian regression
- leydig cells - male sexual differentiation
- Ovary
3
Q
Phenotypic sex
A
The outward appearance of an individual as well as development of sex structures.
