Gestational Trophoblastic Disease 2 Flashcards
Describe the genetics of hydatidiform moles.
1
Q
What are the types of hydatidiform moles? What are the genetics?
A
- Monospermic CHM = 46XX
- loss of maternal chromosomes
- duplication of paternal chromosomes
- Dispermic CHM = 46XX or 46XY
- Diploid biparental CHM = 46XX or 46XY
- ovum from individual with NLRP7 or KHDC3L
- Dispermic PHM = 69XXY
