Gestational Trophoblastic Disease 6 Flashcards
Summarize the most important reasons for gestational trophoblastic neoplasia treatment success.
1
Q
What are the only true prognostic factors of survival in patients with metastatic GTN?
A
- Number of metastases
- Metastatic site other than lung/vagina
- Previously failed chemotherapy
2
Q
What are some success factors that contribute to GTN treatment?
A
- Sensitivity to chemotherapy
- HCG tumor marker
- Referral to or consultation with specialized centers
- Identification of prognostic factors
- Chemotherapy, irradiation, surgery
3
Q
What is involved in the surveillance after GTN?
A
- HCG follow-up: weekly x 4, then monthly x 12
- Contraception x 1 year
- Ultrasound in first trimester of subsequent pregnancies
- Histopathologic examination of products of contraception or placentas from future pregnancies
- HCG 6 weeks after any pregnancy event
