Lecture 12 - enzymes II Flashcards

1
Q

In Lineweaver-Burke, slope is equal to ________

A

Km/Vmax

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2
Q

In Lineweaver-Burke, x-intercept is equal to _______.

A

-1/Km

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3
Q

Bi substrate reactions require ______ of substrates

A

Sequential

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4
Q

Inhibitor binding to the enzymes active site are a hallmark of ______ inhibition

A

Competitive

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5
Q

Inhibitors that bind to an allosteric site are hallmarks of a(n) ________ inhibition

A

Uncompetitive

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6
Q

Inhibitors that bind with either the enzyme or the ES complex is a hallmark of ______ inhibition.

A

Non-competitive

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7
Q

On Lineweaver-Burke, y-intercept is _______

A

1/Vmax

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8
Q

Changes to pH often change enzyme function by ______

A

Altering the 3-D shape of the protein, rendering it non-functional

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