Lecture 4 - Bioinformatics Flashcards Preview

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Flashcards in Lecture 4 - Bioinformatics Deck (6)
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1

In the Blosum-62, what is indicated by a - number when substituting amino acids?

Dissimilar substitution (different chemistries)

2

Substitution introduces AA that is similar in size/chemical properties as the substituted AA

Conservative

3

Substitution introduces AA that is not similar in size/chemical properties as the substituted AA

Non-conservative

4

How many points are awarded for a similar amino acid in the sliding analysis of AAs?

+10

5

How many points are added to gaps in sliding analysis of AAs?

-10

6

In the Blosum-62, what is indicated by a + number when substituting amino acids?

Similar amino acids (regarding chemistry)