Lecture 17 - Membranes II Flashcards
(21 cards)
Plasma membrane fluidity is controlled by:
a) fatty acid composition
b) saturation of fatty acids
c) position of double bonds
d) all of the above
d) all of the above
Which provides more membrane fluidity, cis double bonds or trans double bonds?
cis (produces a bend)
Fatty acids with longer tails have a ____ melting point.
higher
Cholesterol interacts with FA tails and promotes more membrane (fluidity/stiffness)
stiffness
Which of the following will occur quickly after photo bleaching?
a) lateral movement of phosphlipids
b) rapid “flip-flop” from inner to outer membrane, or vice versa.
lateral movement
This cell layer provides signalling functions, cell adhesion functions, and cell identification functions.
glycocalyx
Which membrane of the mitochondria is permeable to most substances?
outer membrane
This structure allows for movement in and out of the nucleus
nuclear pore
Which of the following is not a function of plasma membranes?
a) uptake of molecules
b) transport of molecules
c) degredation of phagocytized molecules
e) release of molecues
degredation of phagocytized molecules
What protein is important in endocytosis?
clathrin
Fusion of membrane bound vesicles to a synaptic neuron are assisted by what protein?
a) FRAP
b) SNARE
c) SOD-1
d) Calmodulin
SNARE
Which of the following is required for proper inner mitochondrial membrane fusion?
a) formation of mitochondria to mitochondria “cross bridges”
b) large electrochemical gradient
c) large [GTP]
d) B & C
D) B & C
This process salvages components of the mitochondria. It requires a sufficient electrochemical gradient and high [GTP] for hydrolysis.
mitochondrial fusion
This “sorts” mitochondria to newly formed daughter cells.
mitochondrial fission
Transport of proteins from ribosomes into the mitochondria is mediated by what protein set?
a) GroEL/GroES
b) HSP-90
c) HSP-70
d) . Tim/Tom System
D) Tim/Tom system
Matrix targeting signals for protein translocation into the mitochondrial matrix are located on the ____ end of the nascent protein.
a) C-terminus
b) N-terminus
c) HSP-70 protein
d) Ribosome
B) N-terminus
Amyloid plaques in mitochondria are a hallmark of this neurodegenerative disease
Alzheimer’s
Destruction of dopaminergic neurons are a hallmark of this neurodegenerative disease.
Parkinson’s
Abnormal trafficking of mitochondria away from the neuronal end are a hallmark of this disease.
Huntington’s
Impairment of the electron transport chain proteins are found in this disease:
a) Alzheimer’s
b) Krutzfeldt-Jakob disease
c) Parkinson’s
d) Huntington’s
C) Parkinson’s
Decreased inner mitochondrial proteins are found in this disease.
Alzheimer’s disease
