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Back up cards AAB > aabhemequick > Flashcards

aabhemequick Flashcards

1
Q

Vit K dependent Prothrombin group factors

A

2,7,9,10

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2
Q

Fibrinogen group, thrombin acts on, used up/not in serum

A

1,5,8,13

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3
Q

Intrinsic, factors…In..it also measures factors..drug it monitors…reagents…NV…phospholipoprotein inhibitor that prolongs aPTT,not corrected by mixing study…

A

8,9,11,12In aPTT it also measures 1,2,5,10heparinphospholipid+ Ca chloride30-36seclupus like anticoagulant

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4
Q

Common factors…measured in both…and….

A

1,2,5,10aPTT,PT

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5
Q

Factors in Contact grp, alternate activation of intrinsic

A

HMWK,PK11,12

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6
Q

extrinsic factors…In…also measures factors..drug names it monitors…reagent…NV….Uses…

A

TF/3, 71,2,5,20warfarin/coumadin thromboplastin10-13secUses INR/ISI

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7
Q

Prothrombinase complex is in common pathway and acts on prothrombin consist of these two factors and these two cofactors…

A

5a, 10acalcium+phospholipid

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8
Q

Protein C degrades…and…Protein…is cofactor that accelates inhibition

A

C degrades 5,8S is cofactor

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9
Q

Primary inhibitor of fibrinolytic system..Principal inhibitor of thrombin/10…

A

fibrinolytic: alpha2 antiplasmin-plasmin is main fibrinolysis agentInhibitor of thrombin/10: anthrombin 3

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10
Q

Labile coag factors…Severe liver disease coag factors..

A

5,81,5

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11
Q

Names:1234578910111213

A

1 fibrinogen2 prothrombin3 Tissue thromboplastin4 calicium5 labile7 stabile8 AHF A9 AHF B, christmas factor10 stuart prower11 AHF C12 Hageman13 fibrin stabilizing

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12
Q

7…9…two names10…12…

A

7: stabile9: ahf B, Christmas 10: stuart prower12: hageman

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13
Q

3 PLT disorders with increased BT and normal PLT ct…3 PLT disorderrs with increased BT and decreased PLT ct…

A

normal PLT:aspirin, vWD, Glanzmannsdecreased PLT:May Hegglin, BS, Wiscott

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14
Q

ITP, TTP, HUS, and DIC all have…PLT cts and …BT

A

decreased PLTs, increased BT

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15
Q

Two disorders with aggregation issues…-primary:-secondary:Two disorders with adhesion issues…

A

aggregation:-primary: Glanzmann only agg with ristocetin-secondary: Wiskott AldrichAdhesion:-vWB, BS

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16
Q

Most common inherited bleeding…2nd most common…Most common acquired inhibitor in hereditary def…Most common PLT disorder…

A

inherited bleeding:most common vWD,second Hemophiliaacquired inhibitor in hereditary def: 8Most common PLT disorder: aspirin

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17
Q

Disorder with no aggregation/flat line with anthing but ristocetin

A

Glansmann

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18
Q

Disorder with abnormal aggregation with most tests, except no aggregation/flat line with collagen

A

aspirin

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19
Q

Two disorders with no aggregation/flat line with ristocetin

A

VWD, BS

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20
Q

Order of hemotopoesis:

A

yolk sac, liver, spleen, BM

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21
Q

Embryonic hmg chains:-Gower 1:-Gower 2:-Portland:Newborn hmg and chains:Adult hmg and chains:

A

Embryonic hmg chains:-Gower 1: zeta, epilson-Gower 2: alpha, epilson-Portland: zeta, gammaNewborn hmg and chains: -F: alpha, gammaAdult hmg, chains, %:-A1: alpha, beta 97%-A2: alpha, delta 2%-F: alpha, gamma 1%Embroyonic has zeta, epilsonAdult has delta

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22
Q

Hmg electrophoresis:Cellulose acetate 8.4:slowest/cathode/- to fastest/anode+

A

Cellulose acetate 8.4:*slow(-) C, S, F, A fast(+)

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23
Q

Acronym for citrate agar 6.2 slowest/cathod to fastest anode…

A

-FASC+

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24
Q

cyanmethmg diluent…separate myoglobin from hmg with…sickle cell reagents, reducer/lyser…

A

cyanmethmg diluent…Drabkinsseparate myoglobin from hmg with…-ammoniun sulfatesickle cell reagents…-reducer: sodium dithionite-lyser: saponin

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25
Q

Cell ct formula…WBC area of 1 square(usually of 4)…RBC/PLT of each tiny square…-RBC usually count 5-PLT usually count all 25 of middle, which equals total of…

A

cells x DF/ total square area (#sqsxarea square) x 0.1WBC 1 square is 1mmRBC/PLT 1 square is 0.04PLTs all 25 is 1mm(one WBC square)

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26
Q

3 things used to create scatterplots…1 not used

A

scatter, volume, conductivitynot fluorescence

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27
Q

Retic % cal…correct retic…RPI:

A

Retics/10retic % x HCT/45RPI: corrected/maturation time factor

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28
Q

WBC correction for NRBCs

A

WBC x 100/NRBC+100

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29
Q

4 things that falsely increase Hmg

A

lipemia, ictericincreased WBC, proteinAll cloud reading

30
Q

Normal MCV, hypochromia due to

A

hyperglycemia

31
Q

Decreased RBC, HCTIncreased MCV/MCHC due to

A

cold agg

32
Q

Decreased RBC, Hmg, HCT…

A

anemia*if hmg high might be lipemia

33
Q

Anemia is below…toddler:female:male:neonates:toddlers have the least, but close to adult femalesneonates have the most

A

Anemia is below…toddler: 12female: 13male: 15neonates: 19

34
Q

Another name for reticulocyte, NVno nucleus, reticulum with supravital stain

A

polychromatophillic erythrocyte, 0.5-1.5%still has RNA, basophillic and orangw

35
Q

2 names for NRBC, last nucleated red cell normally in BM, pyknotic nucleus

A

MetarubricyteOrthochromatic normoblast-more orange due to almost being erythrocyte

36
Q

Alternate name for…1.)Rubriblast2.)Prorubricyte3.)Rubricyteblast before Pro, Pro before, meta after

A

Alternate name for…1.)Rubriblast: Pro-normoblast2.)Prorubricyte: Basophillic normoblast3.)Rubricyte: Polychormatophilic normoblastPro 1st, basophillic, polychromatophilic

37
Q

Stages of WBC:-Stage with primary nonspecific granules-Stage with secondary specific granules, oval nucleus-Stage with kidney bean nucleus

A

-Stage with primary nonspecific granules:Promyelocyte-Stage with secondary specific granules, oval nucleus: Myelocyte-Stage with kidney bean nucleus: metamyelocyte

38
Q

Life span…PLT…RBC…PLTs located, %…

A

PLT 8-11 daysRBC 120PLTs located, %-blood 70%-spleen 30%

39
Q

MCH:calculations, NV

A

MCH: Hmg/RBC x 10 = 28-32 pg-mean cell hmg/rbc-wt

40
Q

Normal values: female versus malesRBC:WBC:Hmg:HCT:

A

RBC: 4-6 million-females 4-5, males 5-6WBC: 4-11 thousandHmg: 12-18-females 13-15-males 14-18HCT: 35-54-females 35-49-males 40-54

41
Q

WBC NV:Total WBC:-absolute is % x totalSegsLymphsMonosBandsEosBaso

A

total wbc: 4-11 thousandSegs: 45-70, mostLymphs: 20-40Monos: 3-10Bands: 0-5Eos: 0-3Baso: 0-2, least

42
Q

Diluent for WBC/PLT cts

A

ammonium oxalate

43
Q

2 normal cells seen in CSF

A

arachnoid and choroidboth very large clumps, pink/blue/purple

44
Q

Normal cell seen in pleural fluid

A

mesothelialnucleated, large, clumped, more round than synovial

45
Q

normal cell seen in synovial/joint

A

synovial cells, nucleated, not as uniform as pleural mesothelial

46
Q

Newborn hmg, %

A

F 50-80A1 20A2 1

47
Q

What 3 things increase WBC

A

NRBC, large platelets, Cryoglobin-Based off granularity, size

48
Q

Schistocytes: affect on RBC, plts

A

RBC decreased because counted as plts

49
Q

3 things decrease plt1 thing increase plt

A

Decrease plt: clumps, satellitosis, giant PLTsIncrease: schistocytes-counted as plts not rbcs

50
Q

Plt ct with sodium citrate DF

A

1.1

51
Q

PAS stains which blasts…Chronic or acute…

A

LymphoblastsAcute

52
Q

conditions with target cells…1 not related to target…

A

Thallesemia, HmgpathiesIDA, post splenectomyLiver disease-Decreased hmgNot myelofibrosis

53
Q

Diluent for wbc, plt…Reagent to diff myoglobin from hmg…

A

Diluent for wbc, plt…ammonium oxalate Reagent to diff myoglobin from hmg…Ammonium sulfate

54
Q

Vit K dependent group called

A

Prothrombin group

55
Q

Citrate agar: 6.2:slowest/cathod- to fastest/anode+

A

Citrate agar: 6.2:*slow(-) F,A,S,Cin some ways opposite of celluose acetate

56
Q

MCV calc, NVRBC side nv

A

MCV: HCT/RBC x 10 = 80-100fL-In a volume of packed rbc, volume of rbc-volume: micro <80, macro>80-RBCs are 6-8 microns, <6 micro,>9macro

57
Q

MCHC: calc, NV

A

MCHC: Hmg/HCT x 100= 32-36%-Hmg concentration in volume-color: hypo <32, hyper >36-percentage so smaller number on top->36 spherocytes

58
Q

RDW: NV, indicates

A

RDW: 11-14.5, diff sizes/anisocytosis >15%

59
Q

HCT: NV…Measures…

A

HCT: 35-54% packed cell volume

60
Q

Hmg electrophoresis:nationality, migrates withD:E:G:

A

D: east indian, D-SE: Southeast asian, E-CG: Blacks, G-S

61
Q

3 things that have leukopenia and 1 that has increased leukocytes

A

decreased:leukemia, viral, chemoincreased:leukemoid rxn

62
Q

Myelocyte maturation from youngest to oldest

A

myeloblastpromyelocyte(pro b4 myelo)myelocytemetamyelocyte(meta after myelo)band

63
Q

6 rbc inclusions

A

HJ bodiesPapemheimer bodies/siderocytes in PBBaso stippling/Shuffners dotsCabot ringHeinz bodies

64
Q

Specific WBC that phagocytizes nucleoprotein in lupus erythematosus

A

NeutrophilLE cellcan also be macrophage

65
Q

Characteristic findings:CLL:CML:ALL:AML:AMML:

A

CLL: smudge cells, sml BlymphsCML: Ph, basophilia, eosinophilia-decreased LAPALL: PAS+, MPO-, TdtAML: Auer rod, trans 8:21AMML: NASDA 3+, NaF 1+

66
Q

what engulfs what…LE:Tart:Mott:

A

what engulfs what…LE: neutrophil,macro engults nucleoprotein-seen in lupusTart: mono/macrophage engulfs nuclearMott: plasma cell engulfs Ig, russel bodies

67
Q

In reactive leukocytosis, absolute GRANULOCYTES are

A

> 7.0

68
Q

ALL: -which one has heterogenous?-which one has vacuolization/abundant cyto?-which one seen in kids/homogenous?L1L2L3

A

L1: homogenous, kidsL2: heterogenous, adultsL3: vacuolization, abundant cyto, homoL1/L2: L is younger than L2, start out homoL3: odd one with vacuoles

69
Q

AML:-granules? least to most?-Auer rod, DIC?-Mono?-Erythroblast? Megakaryoblast?M0:M1:M2:M3:M4/5:M6:M7:

A

AML:M0: no granulesM1: granulesM2: few/trace granulesM3: intense granules, DIC, AuerM4/5: monoM6: erythroblastM7: megakaryoblast

70
Q

Waldenstrom versus Multiple Myeloma:both have increased…and….WM Ig…MM Ig…MM also has…issues

A

both have extra plasma cells/lymphs and rouleauxWM Ig MMM IgG and bone issues

71
Q

Condition with -elevated WBC/segs, increased -ESR/fibrinogen-decreased iron

A

Hodgkins, Reed Sternberg

72
Q

Tears, giant bizarre plts, increased uric acid most ass with

A

myelofibrosis

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