Adaption at birth** Flashcards

1
Q

what does the fetal lung do in utero

A

produce lung fluid which contributes to amniotic fluid

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2
Q

how mania veins and arteries does the placenta heave coming baby

A

1 umbilical vein

2 arteries

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3
Q

how many shunts are there in the fetus and what are they

A

3
ductus arteriosis
ductus venousus
foramen ovale

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4
Q

what does DV do

A

allows oxygenated blood from the placenta to bypass the liver
leads blood into IVC

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5
Q

what does DA do

A

allows most of the blood from the right ventricle to bypass the fetus’s fluid-filled non-functioning lungs
most of the blood goes into the systemic circulation

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6
Q

what does the foramen ovale do

and what is it

A

flat opening in the left ventricle

shunts highly oxygenated blood from right atrium to left atrium

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7
Q

what happens to DA after birth

A

ligamentum arteriorsis

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8
Q

what happens to DV after birth

A

ligamentum teres

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9
Q

what happens to the foramen ovale after birth

A

usually closes

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10
Q

what happens in preparation of birth in terms of lungs

A

surfactant production
in preterm babies mums are given IV dexa to promote surfactant production to reduce the chances of neonatal respiratory distress syndrome

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11
Q

what happens in preparation of birth in terms of glucose

A

accumulation of glycogen to prepare for he disconnection from the placenta
this is in the heart, muscle, liver
also allows them to deal with the stress of labour

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12
Q

what happens in preparation of birth in terms of fat

A

accumulation of brown fat between scapulae and around internal organs to keep them warm

accumulation of subcut fat as well

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13
Q

what hormones are increased in labour and delivery

A

catecholamines and cortisol

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14
Q

colour of the baby when it first comes out - and what happens after it

A
comes out blue
takes a deep breath
cries
goes pinker
cord gets cut
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15
Q

lung aeration when the baby first comes out - steps

A

cold when baby comes out
baby becomes more hypoxic because placenta disconnected
CO2 levels rise allowing them to breathe by crying
breathing pushes the pulmonary fluid out of the lungs into the lymphatic tissue

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16
Q
what happens during circulatory transition
what resistance drops and why
which leads to what
what resistant rises
which leads to the closing of what
A

pulmonary resistance drops because baby starts to breathe

blood starts to circulate through the lungs and needs all of the circulation to go through and not just 7%

systemic vascular resistance rises because the cord is cut leading to oxygen tension rising

left sided pressure increases leading to the closure of FO

17
Q

what things lead to the cut constricting (FO closing)

A

pressure imbalance
increased oxygen
decrease prostaglandins due to disconnected placenta

18
Q

when might the duct tissue not constrict
what can this lead to
what is the treatment

A

in preterm babies as the tissue is not mature enough to close properly

patent ductus arteriosis

NSAIDs as this decreases the level of prostaglandins

19
Q

what is persistent pulmonary tension of the newborn

A

if the pulmonary vascular resistance fails to drop
blood will still cross from right to left via the foramen ovale
baby will stay blue

20
Q

what are the causes of persistent pulmonary tension of the newborn

A

sick, septic, asphyxiated, unwell, idiopathic

21
Q

dx of persistent pulmonary hypertension

A

sats probe on pre ductal such as the right arm and on post ductal feet
usually 20% difference

22
Q

treatment of persistent pulmonary hypertension of the newborn

A

ventilation with a tube
oxygen
sedation
warm
inotropes if theres any myocardial dysfunction
nitric acid - if the above does work - vasodilator for the lungs
ECLS - last line - take the blood out of the baby and oxygenate it then put it back in

23
Q

how long does transient tachypnoea last

who does it occur in and why

A

benign, self limiting, resolves in around 24 hours

C section babies - they take longer to reabsorb all the lung fluid

24
Q

why do babies lose a lot of heat when they are born and through which ways do they lose heat

A

large surface area
wet when born
conduction, convection, evaporation, radiation

25
how to keep the baby warm
hat, blanket, skin-to-skin with the mum, heated mattress, incubator
26
which babies get hypothermia and what can this lead to
premature babies that are small predisposes to other problems
27
what does little oral intake of milk in the first few hours of life lead to in the baby
a drop in insulin and an increase in glycogen and use of hepatic glycogen stores
28
how are babies adapted to dealing with hypoglycaemia
use ketones as brain fuel
29
which babies get hypos
babies who are unwell due to increased energy demands maternal DM/hyperinsulinaemia small/premature babies have low glycogen stores drugs in the mother such as labetalol
30
what does breast feeding reduce the risk of in the mum | why is breast feeding good for the baby
reduced risk of ovarian and breast cancer | transfer of immunoglobulins to the baby[colesterum]
31
what % weight loss does a baby have to lose to be at risk | and at risk of what
10% | risk of dehydration and become hypernatraemic
32
what is the difference between fetal haemoglobin and adult haemoglobin
fetal Hb has a higher affinity for oxygen
33
what happens to fetal hb when the baby is born
it is broken down and replaced by adult haemoglobin
34
how long is it normal to be anaemic in babies and why
8-10 weeks | as adult hb production catches up
35
why can unconjugated jaundice occur in babies
due to breakdown of RBCs
36
very high levels of bilirubin can lead to what
bilirubin encephalopathy
37
when is jaundice bad
<24 hours | prolonged - longer than 14 days in term and longer than 21 days in preterm