Breast histology* Flashcards Preview

Repro > Breast histology* > Flashcards

Flashcards in Breast histology* Deck (26):
1

how many lobes is the secretary breast tissue made of

15-25

2

what each lobe consist of

compound tubulo acinar gland which drains via a series of ducts leading to the nipple

3

what is adjacent to the secretory lobules and what is it surrounded by

dense fibrous tissue surrounded by adipose tissue

4

what are suspensor ligaments of cooper

increased condensations of fibrocollagenous tissue that extend to the dermis of the skin and support the breast

5

where do the lactiferous ducts start and end

branch from each lobule and end at the end of the nipple

6

what do terminal ducts lead into and then what and then

interlobular collecting duct and then extra lobular collecting duct which then leads to lactiferous duct. this then leads to the nipple and passes through a sinus

7

what is the lactiferous sinus

the duct expands for a short distance and then gets smaller again - allows a reserver for milk to build up for breastfeeding

8

what is the lining of larger ducts

columnar epithelium

9

what is the lining of secretary acini

cuboidal or low columnar epithelium

10

what are both larger ducts and secretary acini surrounded by

myoepithelial cells - contractile epithelial cells

11

what do breast glands look similar to

sweat glands

12

what is the nipple covered by

high pigmented keratinized stratified squamous epithelium

13

what is the core of the nipple

dense irregular connective tissue mixed with bundles of smooth muscle

14

why is smooth muscle in the core of the nipple

for nipple erection

15

what can be seen in a transverse section through the nipple (2)

lactiferous sinuses
sebaceus glands which produce oil to help with the protection of the nipples during breastfeeding

16

what happens to the lining of the lactiferous duct as it reaches the surface

changes from being one cell thick to stratified columnar epithelium to stratified squamous epithelium

17

what happens to the epithelial cells during the luteal phase

increase in height
lamina of ducts becomes enlarged and small secretions appear in ducts

18

changed in the mamary glands during the first trimester

elongation and branching of the smaller ducts and proliferation of the epithelial cells of the glands and the myoepithelial cells

19

what changes occur in the second trimester to the mammary gland

tissue continues to develop with differentiation of secretory alveoli
plasma cells and lymphocytes infiltrate the nearby connective tissue

20

what changes occur in the third trimester in the mammary gland

alveoli continue to mature with development of extensive rER

21

what are changes to the mammary gland accompanied

reduction in the amount of connective tissue and adipose tissue present

22

what happens during pregnancy in terms of hormone production

oestrogen and progesterone stimulate proliferation of secretory tissue and fibre fatty tissue becomes sparse

23

composition of human milk

88% water
1.5% protein (daily lactalbumin and casein)
7% carbohydrate (daily lactose)
3.5% lipid

small amounts of ions, vitamins and IgA antibodies

24

how does apocrine secretion take place

lipid droplets bud off from mammary acini and end up as almost vesicles with surrounding membrane

25

how does merocrine secretion take place

proteins in milk are made rER packaged by golgi and secreted as vesicles which merge with apical membrane to release their content into the duct system

26

what happens to the secretory cells of the TDLU following menopause and what happens to the connective tissue

secretory cells degenerate leaving one ducts
connective tissue - fewer fibroblasts and reduced collagen and elastic fibres