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Flashcards in Breast cancer Deck (17)
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1
Q

risk factors

A
personal history of breast cancer
genetic mutation BRAC1 BRAC2
FH of breast/ovarian cancer
prior breast irradiation at young age
childbearing absent or after 30
early periods/late menopause
hot
high BMI
high alcohol intake
2
Q

fibrocystic changes

associated with what

A

benign
lumpiness
thickening
swelling

women period

3
Q

fibroadenomas

who

A

solid round rubbery lump that moves under the skin when touched - mouse

young women

4
Q

infections

A

red, warm, tender, lumpy

5
Q

micro calcifications

A

tiny deposits of calcium - majority are harmless

small % may be cancerous

6
Q

screening

A

mam
50-70s
every 3 years

7
Q

what does triple assessment include

A

clinical exam
imaging
fine needle aspiration/biopsy core

8
Q

what happens when cancer is confirmed

A

CT for staging/MRI

9
Q

radiotherapy following breast conservation surgery - just breast alone

A

negative sentinel biopsy
noted conning micro metastases 0.2-2mm in SNB
or < 4nodes in an adequate axillary node clearance

10
Q

radio following breast conservation - boost to tumour bed for women

A

under 54 on the day of surgery

posterior margin <1mm for invasive disease after full thickness incision

11
Q

radio following mastectomy - chest wall radio

A

tumour >5cm
4 or more nodes involved
involved resection margins
T4 disease

12
Q

radio to ipsilateral axilla

A

> 1 positive macro metastases sentinel node

extensive ECS post axillary clearance

13
Q

radio to the supraclavicular fossa

A

4 or more nodes involved

14
Q

adjuvant treatment

A

tamoxifen - 10 years

letrozole - 5 years

15
Q

who is trastuzumab given to

A

whose cancer cells express HER2-neu as measured by IHC or FISH

16
Q

what should be considered for locally advanced cancer and for who

A

radio as initial therapy for

a primary tumour that is considered inoperable

for patients still inoperable following primary systemic therapy

consider post surgery for all px

17
Q

how should px with T>4b tumours be treated

A

with 0.5cm bolus following mastectomy to increase the skin dose