ANS Pharmacology Flashcards
(39 cards)
1
Q
prazosin, terazosin, doxazosin target role
A
- alpha 1 - antagonist
2
Q
sympathetic function
A
- stimulates smooth muscle contraction - stimulates smooth muscle relaxation - stimulates SA/AV node depolarization
3
Q
M3 receptor role
A
- secretion - smooth muscle contraction
4
Q
vascular contraction and dilation are regulated normally by which parasympathetic receptors
A
- none!
5
Q
problems with parasympathetic drugs
A
- toxicities may be a problem
6
Q
beta 1 antagonist role
A
- decreased cardiac output
7
Q
sympathetic hormones
A
- epineprhine - norepinephrine
8
Q
alpha 2 role
A
- smooth muscle contraction
9
Q
alpha 1 receptor role
A
- smooth muscle contraction
10
Q
M2 antagonist role
A
- increased cardiac output
11
Q
route of administration of parasympathetic drugs
A
- route of admin is key
12
Q
beta 1 role
A
- SA/AV node depolarization
13
Q
M2 receptor role
A
- inhibits SA/AV node depolarization
14
Q
dobutamine target role
A
- beta 1 - agonist
15
Q
parasympathetic hormones
A
- acetylcholine
16
Q
beta 2 agonist vascular drugs
A
- none
17
Q
M2 agonist drug
A
- none
18
Q
acetylcholine receptors
A
- M2 and M3
19
Q
M2 antagonist drugs
A
- atropine - glycopyrrolate
20
Q
beta 1 antagonist drugs
A
- metoprolol - atenolol “LOL” WE’RE ANTAGONIST YOU, YOU BETA MALE THINKING YOU’RE #1
21
Q
phenylephrine target role
A
- alpha 1 - agonist
22
Q
beta 1 agonist roles
A
- SA/AV node depolarization - increased HR - increased cardiac output
23
Q
beta 1 agonist drugs
A
- dobutamine - isoproterenol
24
Q
sympathetic receptors
A
- alpha 1 and 2 - beta 1 and 2
25
dominant sympathetic receptor on the heart role
- beta 1 - increase HR
26
selectivity of parasympathetic drugs
- nonselective for M1-M5
27
beta 2 antagonist vascular drugs
- none
28
parasympathetic function
- stimulates secretion from glands - stimulates smooth muscle contraction - inhibits SA/AV node depolarization
29
beta 2 role
- smooth muscle relaxation
30
vascular contraction and dilation are regulated normally by which sympathetic receptors which cause which one wins?
- alpha 1 - vasoconstriction - increase BP - beta 2 - vasodilation - decrease BP - more alpha 1 than beta 2 so alpha 1 wins
31
dominant parasympathetic receptor on the heart role
- M2 - decrease HR
32
isoproterenol target role
- beta 1, 2, 3 - agonist
33
epinephrine target role
- alpha 1,2 - beta 1,2 - agonist
34
norepinephrine target role
- alpha 1,2 - beta 1,3 - agonist
35
autonomic functions in all organ systems
- secretion - smooth muscle contraction - smooth muscle relaxation - AV/SA node changes in cardiac myocyte
36
M2 agonist role
- SA/AV node hyperpolarization - decreased HR - reduced cardiac output
37
selectivity of sympathetic drugs
- selective for single receptors or a subset of receptors
38
alpha 1 antagonists vascular drugs
- prazosin - terazosin - doxazosin
39
clonidine target role
- alpha 2 presynaptic - agonist
