Beta-lactams I Flashcards Preview

Pharmacology Fall 2016 > Beta-lactams I > Flashcards

Flashcards in Beta-lactams I Deck (20):
1

What are the 3 potentiators of penicillins?

1. Clavulanate
2. Sulbactam
3. Tazobactam

2

What is the mechanism of action for amoxicillin?

Inhibit cell wall synthesis by inhibiting cross-linking of peptidoglycans

3

What is the spectrum of amoxicillin?

Gram (-) aerobes and all gram (+)

4

What are the 3 side effects of amoxicillin?

1. Anaphylactic rxns
2. Endotoxic shock
3. Coagulopathy

5

Is amoxicillin well-absorbed orally or not?

Yes

6

Name 2 side effects of procaine penicillin in the horse?

1. CNS excitement
2. Hemolytic anemia

7

Other than amoxicillin and clavulanic acid, what 3 combinations work well together?

1. Ampicillin - sulbactam
2. Ticarcillin - clavulanic acid
3. Pipercillin - tazobactam

8

What are the 2 anti-staph aureus penicillins?

1. Cloxacillin
2. Methicillin

9

What are the 2 anti-pseudomonas penicillins?

1. Piperacillin
2. Ticarcillin

10

Which penicillin is beta-lactamase resistant?

Temocillin

11

Against which quadrants are benzylpenicillins effective?

1. ALL anaerobes
2. Gram (+) aerobes

12

The spectrum of amoxicillin, ampicillin, and hetacillin are extended from that of penicillin G how?

Includes gram (-) aerobes

13

With which 2 penicillins can clavulanic acid be paired?

1. Amoxicillin
2. Ticarcillin

14

What are the 5 uses of amoxicillin?

1. Canine & feline pyoderma
2. Cat bite abscesses
3. Wounds
4. Kitten URI
5. UTI

15

What are the 3 uses of ampicillin?

1. Bovine respiratory disease
2. Clostridia
3. Mastitis

16

What would you use to treat Pseudomonas otitis?

Ticacillin + clavulanic acid

17

What are the 6 groups of penicillins?

1. Benzylpenicillins
2. Oral penicillins
3. Anti-staph aureus
4. Extended spectrum
5. Anti-pseudomonas
6. Beta-lactamase resistant

18

What is the spectrum of benzylpenicillins?

All anaerobes and gram (+) aerobes

19

What are 2 examples of benzylpenicillins?

1. Benzathine
2. Penicillin G

20

Which group of penicillins can NOT be administered orally?

Anti-staph aureus penicillins: Cloxacillin and methicillin