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Pharmacology Fall 2016 > Introduction > Flashcards

Flashcards in Introduction Deck (32):
1

What are the (7) gram +, aerobic bacteria?

1. Staphylococcus
2. Streptococcus
3. Rhodococcus
4. Listeria monocytogenes
5. Erysipelothrix rhusiopathiae
6. Truperella pyogenes
7. Bacillus anthracis

2

What is the gram +, anaerobic bacteria?

Clostridium

3

What are the (9) gram -, aerobic bacteria?

1. Bordetella
2. Pseudomonas
3. Pasteurella
4. E. coli
5. Klebsiella
6. Salmonella
7. Haemophilus
8. Moraxella
9. Campylobacter

4

What are the (4) gram -, anaerobic bacteria?

1. Brachyspira
2. Dichelobacter
3. Bacteroides
4. Fusobacterium

5

Which of the following is associated with a low volume of distribution: water solubility OR lipid solubility?

Water solubility

6

What are the 4 drug classes that are of LOW volume of distribution?

1. Aminoglycosides
2. Aminocyclitols
3. Penicillins
4. Sulfadimethoxine

7

What are the 3 drug classes that are of MEDIUM volume of distribution?

1. Some cephalosporins
2. Tetracyclines
3. Sulfadiazine

8

What are the 5 drug classes that are of HIGH volume of distribution?

1. Macrolides
2. Doxycycline
3. TMPS
4. Fluoroquinolones
5. Florfenicol

9

What 2 drug classes are based on their concentration above MIC?

1. Aminoglycosides
2. Ketolides

10

What 6 drug classes are based on their time above MIC?

1. Beta-lactams
2. Cephalosporins
3. Macrolides
4. Lincosamides
5. Sulfonamides
6. Tetracyclines

11

What drug class is based on its AUC above MIC?

Fluoroquinolones

12

What are the 4 classes of bactericidal antimicrobials?

1. Beta-lactams
2. Aminoglycosides
3. Nitrofurans
4. Fluoroquinolones

13

What are the 4 classes of bacteriostatic antimicrobials?

1. Sulfonamides
2. Tetracyclines
3. Macrolides
4. Chloramphenicol

14

What are the 3 adverse effects in the dog associated with sulfa-related drugs?

1. Hepatotoxicity
2. KCS (dry eye)
3. Bone marrow suppression

15

What are the 6 drugs that cause diarrhea in the horse?

1. Tetracyclines
2. Macrolides
3. Florfenicol
4. K-Pen
5. Ceftiofur
6. Lincosamides

16

Which drug can cause esophageal erosions in cats?

Doxycycline

17

Which drug class should not be administered to growing pups, kittens, or foals?

Fluoroquinolones

18

What 3 drug classes can cause renal failure?

1. Aminoglycosides
2. Tetracyclines
3. Sulfa crystalluria

19

Which drug class can cause ototoxicity in dogs, cats, horses, and rabbits?

Aminoglycosides

20

What drug causes hyperthermia in the horse?

Erythromycin

21

Which drugs are lethal in the horse?

1. Doxycycline IV
2. Procaine penicillin IV
3. Monensin in feed

22

Which drug is lethal in the pig?

Tilmicosin IV or parenteral

23

Which antimicrobials are banned for extralabel use in food animals?

1. Chloramphenicol
2. Fluoroquinolones
3. Ceftiofur
4. Nitroimidazoles
5. Dimetridazole
6. Ipronidazole
7. Nitrofurazones
8. Glycopeptides
9. Sulfonamides (lactating dairy cattle)

24

What 5 compounds are potential risks to humans?

1. Tilmicosin
2. Carbapenems
3. Glycopeptides
4. Chloramphenicol
5. Prostaglandins

25

Why is Tilmicosin a risk to human health?

Cardiotoxic

26

Why are Carbapenems and Glycopeptides risks to human health?

Antimicrobial resistance

27

Why is Chloramphenicol a risk to human health?

Aplastic anemia

28

Why are Prostaglandins a risk to human health?

Induce parturition in pregnant women

29

Which 2 drugs would be ineffective in the presence of pus or debris?

1. Sulfas

2. AGs

30

Which drug would be ineffective in an aerobic environment?

Nitroimidizaoles

31

Which 3 drugs would be ineffective in an anaerobic environment?

1. AGs

2. FQs

3. Sulfas

32

Which 4 drugs would be the "go-to's" when treating an infection within a "privileged site"?

1. Quinolones

2. Chloramphenicol

3. Florfenicol

4. Macrolides