Biochemistry week 15 Flashcards
(6 cards)
1
Q
What are pyrimidne bases used to build
A
nucleotides such as UMP, CMP and dTMP
2
Q
What happens in the pyrmidine salvage pathway
A
It recycles frr pyrimdine bases to form nucleotides
3
Q
How are pyrimidines degraded
A
- The pyrimidine ring is opened and broken down itno a highly solubel end product
4
Q
What is the end product of pyrimidine degredation+ what are they further broken down into
A
- B-alanine
B-aminoisobutyrate
-Then further brokenr down into Ammonia(Nh3 and CO2
5
Q
What is heriditary Orotic aciduria caused by
A
Deficiency of orotate phosphorinosyltransferae(ORPT) or orotidylate decarboxylase (ODC)
6
Q
What are symptoms of heridtary orotic aciduria
A
Megoblastic anemia m poor growth and orotic acid cyrstals in urine
