Blood physiology/ hematology Flashcards

lab practical 1 (38 cards)

1
Q

transport functions of blood

A
  1. delivering oxygen and nutrients to body tissues
  2. disposal of waste products
  3. transporting hormones to various parts of the body to regulate organ function
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2
Q

other functions of blood

A
  1. regulating internal body temperature
  2. body defense to prevent infection
  3. acid-base balance
  4. blood clotting to prevent blood loss after a blood vessel wall is torn or damaged
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3
Q

3 types of blood cells

A

erythrocytes
leukocytes
thrombocytes

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4
Q

erythrocytes

A

responsible for the transport of oxygen to body tissues and removal of carbon dioxide waste

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5
Q

leukocytes

A

defend the body from viruses, bacteria, and other pathogens/microorganisms that can cause infection

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6
Q

thrombocytes

A

help prevent blood loss by forming collections of cells at the site of a damage called clots when blood vessel walls are torn

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7
Q

why are erythrocytes and thrombocytes not considered true cells

A

no nuclei
unable to mitotically divide

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8
Q

blood cell production is called

A

hematopoiesis

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9
Q

erythrocyte blood cell values

A

males : 5.4 +/- 0.8 million per cubic millimeter (mm3)
females : 4.8 +/- 0.6 million per cubic millimeter (mm3)

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10
Q

leukocytes blood cell values

A

males : 7-9000 per mm3
females : 5-7000 per mm3

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11
Q

thrombocyte blood cell values

A

150,000-400,000 per mm3
average: 300,000 per mm3

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12
Q

hemoglobin

A

molecule in erythrocytes
responsible for binding and carrying oxygen to the body tissue cells and removinh carbon dioxide

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13
Q

polycythemia

A

a person has an abnormally high number of red blood cells

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14
Q

causes of polycythemia

A

bone marrow disease
kidney disease
liver disease
drug use

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15
Q

anemia

A

an abnormal decrease of erythrocytes

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16
Q

anemic hypoxia

A

shortage in oxygen delivery to the body tissue cells

17
Q

hematocrit

A

percent volume of the blood that is made up of erythrocytes

18
Q

heparin

A

blood samples and hematocrit tubes are treated with this to prevent the formation of clots

19
Q

erythropoietin

A

strictly regulates erythrocyte production
released by kidneys

20
Q

normal hematocrit values

A

males: average - 46%
range - 43-49%
females: average - 41%
range 35-45%

21
Q

why do males have higher hematocrit levels

A

influence of testosterone on the production of erythropoietin

22
Q

hematocrit percentage formula

A

height of red cells (mm)
_______________________________ x 100
height of red cells and plasma (mm)

23
Q

potassium cyanide (KCN)

A

helps measure blood hemoglobin levels

24
Q

when hemoglobin is exposed to KCN

A

produces a color compound called cyanmethemoglobin

25
total blood hemoglobin formula
Hb (g) = blood volume (ml blood) x hemoglobin concentration (g Hb/ ml blood)
26
total O2 carrying capacity formula
total g Hb x 1.34 ml O2/ g Hb
27
blood volume for humans
males: 79 ml blood per kilogram of body weight +/- 10% females: 65 ml blood per kilogram of body weight +/- 10%
28
kg to pound conversion
1 kg = 2.2 lbs
29
two classes of leukocytes
granulocytes agranulocytes
30
3 types of granulocytes
neutrophils eosinophils basophils
31
3 types of agranulocytes
large lymphocytes small lymphocytes monocytes
32
neutropenia
low number of neutrophils caused by: genetics, chemotherapy, malnutrition, aplastic anemia
33
neutrophilic leukocytosis
high number of neutrophils caused by: sever burn, chronic inflammation, stressful situations
34
lymphocytosis
high number of lymphocytes caused by: physical/emotional stress, fighting illness/infection
35
lymphocytopenia
low number of lymphocytes caused by: viral infection, zinc deficiency, systemic lupus
36
eosinophilia
high number of eosinophils caused by: parasitic infection, allergies, inflammatory bowel disease, asthma, genetics
37
monocytosis
high number of monocytes caused by : tuberculosis, chronic inflammation, heart attacks, smoking
38
normal total leukocyte count
4500-11,000 WBCs per microliter of blood