Cardiovascular 2 Anti-hypertensives Flashcards Preview

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Flashcards in Cardiovascular 2 Anti-hypertensives Deck (135)
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1

Drug class for Propranolol

sympatholytics: peripheral adrenergic 'r' blockers-beta blockers

2

MoA for Propranolol

adrenergic B1 & B2 receptor inhibitor: reduction in myocardial oxygen demand

3

Indications for Propranolol

angina, HTN, tachyarrhythmias, essential tremor, migraine Px, anxiety

4

SE/ADRs for Propranolol

fatigue, sleep disturbance, depression

5

Contra-indications for Propranolol

hypersensitivity, bradycardia, heart block, uncompensated HF, severe depression, bronchospasm

6

Dx-Dx interactions for Propranolol

ethanol (may increase or decrease conc)

7

Monitoring for Propranolol

BP, chest pain, HR, LFTs

8

What might Propranolol mask?

hypoglycemia

9

Drug class for Metoprolol

sympatholytics: peripheral adrenergic 'r' blocker-beta blocker

10

MoA for Metoprolol

selective B1 adrenergic receptor inhibitor

11

Indications for Metoprolol

angina, HTN, hemodynamically stable post MI

12

SE/ADRs for Metoprolol

fatigue, sleep disturbance, depression, bradycardia, rebound angina/HTN, hypotension

13

Contra-indications for Metoprolol

hypersensitivity, bradycardia, heart block, uncompensated heart failure, severe depression

14

Dx-Dx interactions for Metoprolol

multiple

15

Monitoring for Metoprolol

BP, HR, LFTs

16

Drug class for Atenolol

sympatholytics: peripheral adrenergic 'r' blockers-beta blockers

17

MoA for Atenolol

selective B1 adrenergic receptor inhibitor

18

Indications for Atenolol

angina, HTN, hemodynamically stable post MI

19

SE/ADRs for Atenolol

fatigue, sleep disturbance, depression, bradycardia, rebound angina, HTN, hypotension

20

Contra-indications for Atenolol

hypersensitivity bradycardia, heart block, uncompensated heart failure, severe depression

21

Dx-Dx interactions for Atenolol

multiple

22

Monitoring for Atenolol

BP, HR, eGFR

23

Drug class for Prazosin

alpha-blocker

24

MoA for Prazosin

selective alpha1 blocker which relaxes smooth muscle in arteries, veins, & prostate

25

Indications for Prazosin

HTN, off-label: PTSD, Raynaud's phenomenon

26

SE/ADRs for Prazosin

postural hypotension, nausea, drowsiness, syncope, palpitations, dizziness, 'floppy iris' syndrome

27

Contra-indications for Prazosin

orthostatic hypotension

28

Dx-Dx interactions for Prazosin

PDE-5 blockers (Tadalafil), anti-hypertensive meds

29

Monitoring for Prazosin

BP, BUN, eGFR, syncopal episodes

30

PG category for Prazosin

C but avoid