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Flashcards in Neuro Deck (72)
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1

Drug class for Lamotrigine

anti-seizure drug

2

MoA for Lamotrigine

blocks sustained repetitive neurone firing & prolongs inactivations of Na channels & probably Ca channels

3

Indications for Lamotrigine

mono or add-on therapy for generalized or partial seizures

4

Drug class for Carbamazepine

anti-seizure drug

5

MoA for Carbamazepine

decrease synaptic release glutamate, inhibits Na channels

6

Indications for Carbamazepine

generalized tonic-clonic & partial seizures

7

Drug class for Phenytoin

anti-seizure drug

8

MoA for Phenytoin

limits repetitive firing of neurons, inhibits Na channels

9

Indications for Phenytoin

partial & generalized tonic-clonic seizures

10

Drug class for Ethosuximide

anti-seizure drug

11

MoA for Ethosuximide

reduces low threshold Ca currents

12

Indications for Ethosuximide

petit mal or absence seizures in children

13

Drug class for Topiramate

anti-seizure drug

14

MoA for Topiramate

reduces voltage-gated Na currents, enhancesGABAa receptor currents, inhibits glutamate receptor

15

Indications for Topiramate

generalized tonic-clonic, partial, absence, migraines, HAs

16

Drug class for Valproic Acid

anti-seizure drug

17

MoA for Valproic Acid

increase concentration GABA pre & post-synaptive sites

18

Indications for Valproic Acid

seizures, primary generalized tonic-clonic, absence, myoclonic, tonic, mania, mood stabilization, migraine Px

19

Drug class for Lorazepam

benzodiazepine

20

MoA for Lorazepam

potentiates GABAa receptor

21

Indications for Lorazepam

anxiety, operative amnesia, status epilepticus

22

Drug class for Donepezil

alzheimer's disease: AChE inhibitors

23

MoA for Donepezil

inhibits activity of acetylcholinesterase thereby raising acetylcholine concentration in hippocampus

24

Indications for Donepezil

mild to moderate dementia of the Alzheimers type

25

Drug class for Memantine

alzheimer's disease: NMDA receptor antagonist

26

MoA for Memantine

blocks NMDA receptor prevention Ca ion influx via the NMDA receptor

27

Indications for Memantine

moderate to severe dementia of the Alzheimers type

28

Drug class for Levodopa/Carbidopa

dopamine

29

MoA for Levodopa/Carbidopa

elevates CNS dopamine levels

30

Indications for Levodopa/Carbidopa

Parkinson's disease