Ch 9 - Virology Flashcards Preview

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Flashcards in Ch 9 - Virology Deck (29)
1

genetic element that cannot replicate independently of a living (host) cell

Virus

2

extracellular form of a virus

virion

3

are most viral genomes circular or linear?

mostly linear

4

the protein shell that surrounds the genome of a virus particle

capsid

5

subunit of the capsid

capsomere

6

complete complex of nucleic acid and protein packaged in the virion

nucleocapsid

7

virus that contains additional layers around the nucleocapsid

enveloped virus

8

viruses lyse host cells after infection

virulent mode

9

viruses replicate their genomes in tandem with host genome and without killing host

temperate mode

10

state where most virus genes are not expressed and virus genome (prophage) is replicated in synchrony with host chromosome

lysogeny

11

a bacterium containing a prophage

lysogen

12

release of virions from host cell does not result in cell lysis

persistent infections

13

delay between infection by the virus and lytic events

latent infections

14

conversion of normal cell into tumor cell

transformation

15

two or more cells become one cell with many nuclei

cell fusion

16

give an example of a retrovirus (ssRNA)

HIV

17

give an example of a hepadnavirus (dsDNA)

hepatitis B

18

Attachment of the virus to a susceptible host cell

adsorption

19

Entry of the virion or its nucleic acid

penetration

20

what are the phases of viral replication?

1) attachment
2) entry
3) synthesis of nucleic acids & proteins
4) assembly of capsids
5) release (lysis)

21

two phases of the latent period

eclipse and maturation

22

number of virions released

burst size

23

proteins necessary for replication of virus nucleic acid

early proteins

24

proteins that make up the structural components

late proteins

25

these viruses can undergo a stable genetic relationship within the host

temperate

26

viruses that are parasitic on other viruses

defective viruses

27

infectious RNA molecules that lack a protein coat

viroids

28

infectious proteins whose extracellular form contains no nucleic acid

prions

29

these infectious proteins infect the PrnP gene

prions