Flashcards in Lecture 20 - Immunity (inborn) & 21 Deck (47)
enzyme that Breaks down peptidoglycan
enzyme that is an Iron-chelator
enzyme that Produces superoxide radicals
what causes the unusual conformation in antimicrobial peptides?
cross-linking and excess proline
what are the two types of monocytes?
dendritic cells and macrophages
what are the two types of granulocytes?
neutrophils & mast cells
What are the two types of lymphocytes?
T-cell and B-cell
these are Characterized by stainable granules
these are Active phagocytes that do not enter tissues
these cells are Most often associated with allergic response
tissue associated cells that are active in phagocytosis
phagocytic cells that are more closely associated with presenting antigens to leukocytes
what is the first response to infection?
A group of approximately 30 soluble & membrane-bound proteins that recognizes immune complexes or cell surfaces of bacteria
which complement pathway requires an antibody?
marking/targeting of bacteria for destruction
C3a is a mediator of _______
C3b is a mediator of ________
how do macrophages recognize microbes when they lack antibodies?
pattern recognition receptors
conserved recognition motifs are called
pathogen-associated molecular patterns (PAMPs)
what are the two types of bacterial killing in the phagolysosome?
oxidative and non-oxidative killing
recognizes complex of viral peptide with MHC I and kills infected cell
Cytotoxic T Cell
recognizes complex of bacterial peptide with MHC II and activates macrophage
recognizes complex of antigenic peptide with MHC II and activates B cell
Helper T cell
Activates killing response in phagocytic cells
Effective at killing intracellular pathogens that are phagosome-bound
Stimulates innate response
Activates plasma cell differentiation in response antibody-bound antigen
Induces production of antibody