Lecture 18 - Ch 27 - Microbial Interactions with Humans Flashcards
(12 cards)
Microorganisms usually found associated with human body tissue
normal microbial flora
The decrease or loss of virulence
attenuation
Organism causes disease by means of a toxin that inhibits host cell function or kills host cells
toxicity
Ability of a pathogen to grow in host tissue at densities that inhibit host function
Invasiveness
Proteins released from the pathogen cell as it grows
exotoxins
what are the 3 types of exotoxins?
Cytolytic toxins
AB toxins
Superantigen toxins
which type of toxins are responsible for cell lysis?
Type II - membrane disrupting toxins
which type of toxins use enzymatic activity?
Type III - A-B Toxins
What are type I toxins?
Superantigens
What is an example of a superantigen?
Toxic Shock Syndrome (from Staphylococcus aureus)
What is the name of the endotoxin?
lipopolysaccharide (LPS)
Where do endotoxins attach to a cell?
the membrane of Gram (-) bacteria