classic presentations 2 Flashcards Preview

2016 Rapid Review! > classic presentations 2 > Flashcards

Flashcards in classic presentations 2 Deck (40):
1

Dry eyes, dry mouth, arthritis

Sjögren syndrome (autoimmune destruction of exocrine glands)

2

Dysphagia (esophageal webs), glossitis, iron deficiency anemia

Plummer-Vinson syndrome (may progress to esophageal squamous cell carcinoma)

3

Elastic skin, hypermobility of joints,bleeding tendency

Ehlers-Danlos syndrome (type V collagen defect, type III collagen defect seen in vascular subtype of ED)

4

Enlarged, hard left supraclavicular node

Virchow node (abdominal metastasis)

5

Episodic vertigo, tinnitus, hearing loss

Meniere disease

6

Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells

Mycosis fungoides (cutaneous T-cell lymphoma) or Sézary syndrome (mycosis fungoides + malignant T cells in blood)

7

Facial muscle spasm upon tapping

Chvostek sign (hypocalcemia)

8

Fat, female, forty, and fertile

Cholelithiasis (gallstones)

9

Fever, chills, headache, myalgia following antibiotic treatment for syphilis

Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in endotoxin release)

10

Fever, cough, conjunctivitis, coryza, diffuse rash

Measles

11

Fever, night sweats, weight loss

B symptoms (staging) of lymphoma

12

Fibrous plaques in soft tissue of penis with abnormal curvature

Peyronie disease (connective tissue disorder)

13

Golden brown rings around peripheral cornea

Wilson disease (Kayser-Fleischer rings due to copper accumulation)

14

Gout, intellectual disability, self-mutilating behavior in a boy

Lesch-Nyhan syndrome (HGPRT deficiency, X-linked recessive)

15

Hamartomatous GI polyps, hyper pigmentation of mouth/feet/hands/genitalia

Peutz-Jeghers syndrome (inherited, benign polyposis can cause bowel obstruction;cancer risk, mainly GI)

16

Hepatosplenomegaly, pancytopenia, osteoporosis, aseptic necrosis of femoral head, bone crises

Gaucher disease (glucocerebrosidase deficiency)

17

Hereditary nephritis, sensorineural hearing loss, cataracts

Alport syndrome (mutation in collagen IV)

18

Hyperphagia, hypersexuality, hyperorality, hyperdocility

Klüver-Bucy syndrome (bilateral amygdala lesion)

19

Hyperreflexia, hypertonia, Babinski sign present

UMN damage

20

Hyporeflexia, hypotonia, atrophy, fasciculations

LMN damage

21

Hypoxemia, polycythemia, hypercapnia

Chronic bronchitis (hyperplasia of mucous cells, “blue bloater”)

22

Indurated, ulcerated genital lesion

Nonpainful: chancre (1° syphilis, Treponema pallidum) Painful, with exudate: chancroid (Haemophilus ducreyi)

23

Infant with cleft lip/palate, microcephaly or holoprosencephaly, polydactyly, cutis aplasia

Patau syndrome (trisomy 13)

24

Infant with hypoglycemia, hepatomegaly

Cori disease (debranching enzyme deficiency) or Von Gierke disease (glucose-6-phosphatase deficiency, more severe)

25

Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart defect

Edwards syndrome (trisomy 18)

26

Jaundice, palpable distended non-tender gallbladder

Courvoisier sign (distal malignant obstruction of biliary tree)

27

Large rash with bull’s-eye appearance

Erythema chronicum migrans from Ixodes tick bite (Lyme disease: Borrelia)

28

Lucid interval after traumatic brain injury

Epidural hematoma (middle meningeal artery rupture)

29

Male child, recurrent infections, no mature B cells

Bruton disease (X-linked agammaglobulinemia)

30

Mucosal bleeding and prolonged bleeding time

Glanzmann thrombasthenia (defect in platelet aggregation due to lack of GpIIb/IIIa)

31

Muffled heart sounds, distended neck veins, hypotension

Beck triad of cardiac tamponade

32

Multiple colon polyps, osteomas/soft tissue tumors, impacted/ supernumerary teeth

Gardner syndrome (subtype of FAP)

33

Myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance

Pompe disease (lysosomal α-1,4-glucosidase deficiency)

34

Neonate with arm paralysis following difficult birth

Erb-Duchenne palsy (superior trunk [C5–C6] brachial plexus injury: “waiter’s tip”)

35

No lactation postpartum, absent menstruation, cold intolerance

Sheehan syndrome (pituitary infarction)

36

Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia

Multiple sclerosis

37

Painful blue fingers/toes, hemolytic anemia

Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumoniae, infectious mononucleosis, CLL)

38

Painful fingers/toes changing color from blue to white to red with cold or stress

Raynaud phenomenon (vasospasm in extremities)

39

Painful, raised red lesions on pads of fingers/toes

Osler nodes (infective endocarditis, immune complex deposition)

40

Painless erythematous lesions on palms and soles

Janeway lesions (infective endocarditis, septic emboli/ microabscesses)