classic/relevant treatments 2

Question 1

Hypercholesterolemia

Answer 1

Statin (first-line)

Question 2

Hypertriglyceridemia

Answer 2

Fibrate

“Vibrates” lower VDLDs (TGs)

Question 3

Immediate anticoagulation

Answer 3

Heparin

Question 4

Infertility

Answer 4

Leuprolide, GnRH (pulsatile), clomiphene

Question 5

Influenza

Answer 5

Oseltamivir, zanamivir

Question 6

Kawasaki disease

Answer 6

IVIG, high-dose aspirin

Question 7

Legionella pneumophila

Answer 7

Macrolides (eg, azithromycin)

Question 8

Long-term anticoagulation

Answer 8

Warfarin, dabigatran, rivaroxaban and apixaban

Question 9

Malaria

Answer 9

Chloroquine, mefloquine, atovaquone/proguanil (for blood schizont), primaquine (for liver hypnozoite)

Question 10

Malignant hyperthermia

Answer 10

Dantrolene

Question 11

Medical abortion

Answer 11

Mifepristone

Question 12

Migraine

Answer 12

Abortive therapies (eg, sumatriptan, NSAIDs); prophylaxis (eg, propranolol, topiramate, CCBs, amitriptyline)

Question 13

Multiple sclerosis

Answer 13

Disease-modifying therapies (eg, β-interferon, natalizumab); for acute flares, use IV steroids

Question 14

Mycobacterium tuberculosis

Answer 14

RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)

Question 15

Neisseria gonorrhoeae

Answer 15

Ceftriaxone (add doxycycline to cover likely concurrent C trachomatis)

Question 16

Neisseria meningitidis

Answer 16

Penicillin/ceftriaxone, rifampin (prophylaxis)

Question 17

Neural tube defect prevention

Answer 17

Prenatal folic acid

Question 18

Osteomalacia/rickets

Answer 18

Vitamin D supplementation

Question 19

Osteoporosis

Answer 19

Calcium/vitamin D supplementation (prophylaxis); bisphosphonates, PTH analogs, SERMs, calcitonin,
denosumab (treatment)

Question 20

Patent ductus arteriosus

Answer 20

Close with indomethacin; keep open with PGE analogs

Question 21

Pheochromocytoma

Answer 21

α-antagonists (eg, phenoxybenzamine)

Question 22

Pneumocystis jirovecii

Answer 22

TMP-SMX (prophylaxis and treatment in immunosuppressed patients)

Question 23

Prolactinoma

Answer 23

Cabergoline/bromocriptine (dopamine agonists)

Question 24

Prostate adenocarcinoma/uterine fibroids

Answer 24

Leuprolide, GnRH (continuous)

Question 25

Prostate adenocarcinoma

Answer 25

Flutamide

Question 26

Pseudomonas aeruginosa

Answer 26

Antipseudomonal penicillins, aminoglycosides, carbapenems

Question 27

Pulmonary arterial hypertension (idiopathic)

Answer 27

Sildenafil, bosentan, epoprostenol

Question 28

Rickettsia rickettsii

Answer 28

Doxycycline, chloramphenicol

Question 29

Schizophrenia (negative symptoms)

Answer 29

Atypical antipsychotics

Question 30

Schizophrenia (positive symptoms)

Answer 30

Typical and atypical antipsychotics

Question 31

SIADH

Answer 31

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

Question 32

Sickle cell disease

Answer 32

Hydroxyurea (^fetal hemoglobin)

Question 33

Sporothrix schenckii

Answer 33

Itraconazole, oral potassium iodide

Question 34

Stable angina

Answer 34

Sublingual nitroglycerin

Question 35

Staphylococcus aureus

Answer 35

MSSA: nafcillin, oxacillin, dicloxacillin (antistaphylococcal penicillins); MRSA: vancomycin, daptomycin, linezolid, ceftaroline

Question 36

Streptococcus bovis

Answer 36

Penicillin prophylaxis; evaluation for colon cancer if linked to endocarditis

Question 37

Streptococcus pneumoniae

Answer 37

Penicillin/cephalosporin (systemic infection, pneumonia), vancomycin (meningitis)

Question 38

Streptococcus pyogenes

Answer 38

Penicillin prophylaxis

Question 39

Temporal arteritis

Answer 39

High-dose steroids

Question 40

Tonic-clonic seizures

Answer 40

Levetiracetam, phenytoin, valproate, carbamazepine

Question 41

Toxoplasma gondii

Answer 41

Sulfadiazine + pyrimethamine

Question 42

Treponema pallidum

Answer 42

Penicillin

Question 43

Trichomonas vaginalis

Answer 43

Metronidazole (patient and partner)

Question 44

Trigeminal neuralgia (tic douloureux)

Answer 44

Carbamazepine

Question 45

Ulcerative colitis

Answer 45

5-ASA preparations (eg, mesalamine), 6-mercaptopurine, infliximab, colectomy

Question 46

UTI prophylaxis

Answer 46

TMP-SMX

Question 47

Warfarin reversal

Answer 47

Fresh frozen plasma (acute), vitamin K (non-acute)