classic labs/findings 2 Flashcards Preview

2016 Rapid Review! > classic labs/findings 2 > Flashcards

Flashcards in classic labs/findings 2 Deck (35):
1

Dysplastic squamous cervical cells with “raisinoid” nuclei and hyperchromasia

Koilocytes (HPV: predisposes to cervical cancer)

2

Electrical alternans (alternating amplitude on EKG)

Pericardial tamponade

3

Enlarged cells with intranuclear inclusion bodies

“Owl eye” appearance of CMV

4

Enlarged thyroid cells with ground-glass nuclei with central clearing

“Orphan Annie” eyes nuclei (papillary carcinoma of the thyroid)

5

Eosinophilic cytoplasmic inclusion in liver cell

Mallory body (alcoholic liver disease)

6

Eosinophilic cytoplasmic inclusion in neuron

Lewy body (Parkinson disease and Lewy body dementia)

7

Eosinophilic globule in liver

Councilman body (viral hepatitis, yellow fever), represents hepatocyte undergoing apoptosis

8

Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons

Negri bodies of rabies

9

Extracellular amyloid deposition in gray matter of brain

Senile plaques (Alzheimer disease)

10

Giant B cells with bilobed nuclei with prominent inclusions

Reed-Sternberg cells (Hodgkin lymphoma) (“owl’s eye”)

11

Glomerulus-like structure surrounding vessel in germ cells

Schiller-Duval bodies (yolk sac tumor)

12

“Hair on end” (“Crew-cut”) appearance on x-ray

β-thalassemia, sickle cell disease (marrow expansion)

13

hCG elevated

Choriocarcinoma, hydatidiform mole (occurs with and without embryo, and multiple pregnancy)

14

Heart nodules (granulomatous)

Aschoff bodies (rheumatic fever)

15

Heterophile antibodies

Infectious mononucleosis (EBV)

16

Hexagonal, double-pointed, needle-like crystals in bronchial secretions

Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)

17

High level of d-dimers

DVT, PE, DIC

18

Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)

Ghon complex (1° TB: Mycobacterium bacilli)

19

“Honeycomb lung” on x-ray or CT

Interstitial pulmonary fibrosis

20

Hypercoagulability (leading to migrating DVTs and vasculitis)

Trousseau syndrome (adenocarcinoma of pancreas or lung)

21

Hypersegmented neutrophils

Megaloblastic anemia (B12 deficiency: neurologic symptoms; folate deficiency: no neurologic symptoms)

22

Hypertension, hypokalemia, metabolic alkalosis

1° hyperaldosteronism (Conn syndrome)

23

Hypochromic, microcytic anemia

Iron deficiency anemia, lead poisoning, thalassemia (fetal hemoglobin sometimes present)

24

Intranuclear eosinophilic droplet-like bodies

Cowdry type A bodies (HSV or VZV)

25

Iron-containing nodules in alveolar septum

Ferruginous bodies (asbestosis: ^chance of mesothelioma)

26

Keratin pearls on a skin biopsy

Squamous cell carcinoma

27

Large granules in phagocytes, immunodeficiency

Chédiak-Higashi disease (congenital failure of phagolysosome formation)

28

“Lead pipe” appearance of colon on abdominal imaging

Ulcerative colitis (loss of haustra)

29

Linear appearance of IgG deposition on glomerular and alveolar basement membranes

Goodpasture syndrome

30

Low serum ceruloplasmin

Wilson disease (hepatolenticular degeneration)

31

“Lumpy bumpy” appearance of glomeruli on immunofluorescence

Poststreptococcal glomerulonephritis (due to deposition of IgG, IgM, and C3)

32

Lytic (“punched-out”) bone lesions on x-ray

Multiple myeloma

33

Mammary gland (“blue domed”) cyst

Fibrocystic change of the breast

34

Monoclonal antibody spike ƒ

-Multiple myeloma (usually IgG or IgA)
ƒ-Monoclonal gammopathy of undetermined significance (MGUS consequence of aging)
ƒ-Waldenström (M protein = IgM) macroglobulinemia ƒ
-Primary amyloidosis

35

Mucin-filled cell with peripheral nucleus

“Signet ring” (gastric carcinoma)