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Flashcards in complications of diabetes Deck (17)
1

high blood glu-->____,____,___-->activates____

AGE, DAG, oxidative stress-->PKC beta activation

2

earliest stage of retinal involvemnet

non-proliferative

3

microaneurysms, blot hemorrhages, cotton wool spots

non-proliferative diabetic retinopathy

4

small vessel occlusion and retinal hypoxia, vitrous hemorrhage, retinal detachment

proliferative diabetic retinopathy

5

best tx of reinopathy

prevention

6

recommendations for prevention of retinopathy

dilated eye exam annually starting at 5 yrs post dx

7

tx of macular sparing retinopathy

panretinal xenon/argon laser photocoagulation

8

tx of macular edema

focal laser

9

tx for retinal detachment

surgery

10

prevention of diabetic nephropathy (3)

1. urine albumin annually
2. serum cr @ dx
3. nonpreggers with micro or macroalbuminemia

11

medications that can be used to tx pain assc'd with diabetic neuropathy (4)

1. amitriptyline
2. anticonvulsants (gabapentin)
3. duloxetine
4. topical capsaicin

12

severely neuropathic extremity exposed to trauma, characterized by joint dislocation, fracture, deformity - presents with swelling, incr skin temp, erythema

charcot arthropathy

13

dyxfxn of the cholinergic, NE systems

autonomic neuropathies

14

what sort of tests to check annually in a diabetic

1. eye exam
2. Cr
3. microalbumin
4. foot exam

15

what is the most common cause of death in diabetics

ischemic heart disease

16

what sort of diabetics should receive ASA as prevention?

T2DM men >50, women>60, with at least 1+ risk factor (FHx CVD, HTN, smoking, dyslipidemia, albuminuria

17

is aggressive glycemic control more effective in microvascular or macrovascular complications?

microvascular;
it has NOT been shown to reduce coronary heart disease