pit gland histology Flashcards Preview

Endocrine > pit gland histology > Flashcards

Flashcards in pit gland histology Deck (30)
1

what is superior to the pit gland?

diaphragma sellae and hypothalamus

2

what is inferior to the pit gland?

sella turcica

3

what is lateral to the pit gland?

cavernous sinuses

4

anteroinferior to pit gland?

sphenoid sinus

5

anterosuperior to pit gland?

optic chiasm

6

cavernous sinuses contain what structures?

internal carotids

7

CN __, ____,___ and ____tracts are adjacent to pit gland

III, IV, VI optic tract

8

what division is the anterior and the posterior pituitary derived from?

ectoderm

9

in the development of the pit gland, what is derived directly from the oral ectoderm prior to developing into the anterior lobe?

rathke's pouch

10

the posterior lobe is directly derived from?

neuroectoderm

11

what are the signaling molecules for the development of the pit gland?

BMP-4 + FGF-8

12

Remnants of Rathke’s cleft and the craniopharyngeal duct in children

Craniopharyngioma

13

what does adult Craniopharyngioma develop from?

from mature cells in the anterior hypophysis

14

Superior hypophysial arteries supplies?

anterior pit

15

inferior hypophysial arteries supplies

posterior pit

16

a scant reticulin network in pars distalis characterizes what?

pituitary adenoma

17

what to use if you want to ID hormone that an adenoma is producing (ie. FSH)

immunohistochemistry

18

acidophils that secrete GH?

somatotropes

19

acidophils that secrete prolactin

Mammotropes (lactotropes)

20

what are the only acidophils in the pars distalis?

somatotropes + mammotropes

21

rarely, acidophilic stem cells in a normal pit can synthesize & secrete ____ and _____

GH and prolactin

22

basophils that secrete ACTH and β-lipotrophic hormone

Corticotropes

23

basophils that secrete LH and FSH

gonadotropes

24

ACTH is found where in pit?

mucoid wedge; can invade posterior pit

25

crooke's hyaline change is seen with what?

response of corticotropes to excess glucocorticoids

26

collection of axons whose cell bodies reside in the supraoptic & paraventricular nucleir of the hypothalamus

neurohypophysis

27

what are the support cells of the neurohypophysis

pituicytes

28

paraventricular nucleus makes?

oxytocin

29

supraventricular nucleus makes?

ADH

30

dilatations along the length of the axons in neurohypophysis?

herring body