Flashcards in Pancreas/adrenal Histology Deck (33)
pancreatic islets are derived from____
what provides the supporting framework for pancreatic islets?
pancreatic islets are accompanied by ____and ____
capillaries and ANS fibers
70% of cells in islets are?
where are beta cells located?
scattered throughout, but concentrated in center
tumor that can drive down blood glu levels
where are alpha cells located?
periphery of pancreas
what do alpha cells secrete?
GLUT2 transporter is insulin______
_____may be used to promote insulin secretion in type II diabetics
sulfonylurea receptor inhibitors
name the sulfonylurea receptor inhibitors
role of GLUT2 transport protein
to transport glu into cell in order to stimulate insulin secretion
GLUT4 transporter is insulin_____
adrenal gland outer cortex is derived from_____, inner medulla derived from_____
mesoderm; neural crest cells
what is req'd for differentiation of precursor cells into chromaffin cells? (2)
Superior suprarenal artery branches from what parent artery?
middle suprarenal artery branches from what parent artery?
inferior suprarenal artery branches from what parent artery?
subscapular plexus divides into (2)
1. cortical arteries
2. medullary arteries
in the zona glomerulosa, the secretory prodcts are ____
in the zona fasciculata, the secretory products are
in the zona reticularis, the secretory products are
sex hormones (androgens)
what type of cells are absent in the zona fasciculata?
ACTH has an effect on cells of which compartments (2
1. zona fasciculata
2. zona reticularis
what is the zona glomerulosa under the control of?
chromaffin cells are ____sympathetic neurons, innervated by ____fibers from _____
postganglionic; preganglionic; T8-L1
what enzymes converts NE-->epi?
phenylethanolamine N methyltransferase
phenylethanolamine N methyltransferase requires the presence of?
where does the synthesis or Epi and NE occur?
cytosol of chromaffin
besides the adrenal glands, chromaffin tissue can also be found where?
organ of zuckerkandl
where is the organ of zuckerkandl
at the bifurcation of the aorta and the IMA
a tumor of teh organ of zuckerkandl would be expected to incr the output of?