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Flashcards in hyperthyroidism Deck (27)
1

what Ab can you test for hyperthyroidism?

TSI

2

what antibodies would you find in someone with Graves?

TRAb, TSIg

3

graves opthalmopathy is assc'd with which risk factors? (3)

1. smoking
2. high TSI
3. high I131

4

tx of graves that slow conversion of T4?

1. beta blockers
2. steroids

5

tx of graves that fxn as antithyroids? (2)

1. PTU
2. Methimazole

6

SE assc'd with antithyroids

1. liver toxicity
2. agranulocytosis

7

how long can antithyroid meds be used?

under 2 yrs

8

why tx someone with iodine a week before thyroidectomy?

1. decr T4
2. decr vascularity

9

besides iodine, what else to prescribe person before thyroidectomy?

1. antithyroids
2. beta blockers

10

multiple autonomously functioning nodules that form a toxic goiter

Plummer's disease

11

single autonomously functioning nodule

hot nodule

12

autonomously functioning nodules are typically seen in what patient population?

patients >50

13

uptake and scan with diffuse distribution, normal or high uptake

graves

14

uptake and scan with focal areas of hyperactivity, normal or high uptake

autonomously functioning nodules

15

what is the radioactive tx for hot nodules

radioactive ablation

16

thyroiditis causes thyroid uptake to be ____

low

17

hyperthyroidism with low thyroid uptake

thyroiditis

18

tx of thyroiditis (3)

1. NSAIDS
2. prednisone
3. beta blockers

19

type 1 amiodarone induced hyperthyroidism AKA?

Jod Basedow phenomenon (incr synthesis)

20

mechanisms by which amiodarone causes hyperthyroidism (2)

1. jod basedow phenomenon (type 1 AIH)
2. thyroiditis (type 2)

21

how can you tx type 2 amiodarone hyperthyroidism

steroids

22

what is the only way to decr T4 levels in a person with amiodarone-induced hyperthyroidism?

surgery

23

how to work up TSH producing pit adenoma? (2)

1. high alpha subunit
2. MRI

24

tx of TSH producing pit adenoma (2)

1. surgery via transphenoidal resection
2. octreotide

25

if T4 is elevated in pregnancy, how to tx?

1st trimester: PTU
2nd-3rd trimester: methimazole

26

in euthyroid sick syndrome, TSH is _____, FT4/T3 is ____, rT3 is _____

TSH is low, FT4/T3 is low, rT3 is high

27

tx of euthyroid sick syndrome

none usually