cvs 18 Flashcards

(39 cards)

1
Q

bithermal antibidy

A

IgG

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2
Q

mycoplasma and mononucleosis have these antibodies

A

IgM

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3
Q

which drugs can cause AIHA with IgG DONETH LANDSTEIN ab

A

pennicillin
2/3 penicillin
methyldopa
quinidine

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4
Q

antibodies against GP IIb IIIA

A

ITP

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5
Q

decrease exp of GP IIB IIIA

A

glanzman thrombocytopenia

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6
Q

direct combs test

A

antibody + RBC

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7
Q

indirect comb

A

normal RBC mix with serum of pt (AB)

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8
Q

RSV is most common cause of

A

bronchiolitis in babies

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9
Q

mannifestation and RF of bronchiolitis

A

nasal cong/distress/ flaring
tachypnea
wheezes/ crackles
RF——- prematurity —- resp failure

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10
Q

prophylaxiis for RSV

A

palivizumab —- fusion protein inhibtor

ribavirin (CHAIR mnemonic)

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11
Q

CLL mnemonic

A
HATS
Hypogammaglobulinemia
AIHA
Transf to DLBL
Small lymphocytic lymph

SMUDGE CELLS —- CD5 CD20

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12
Q

mechanism of Denosumab

A

mimics osteoprotegrin !! — acivates clast

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13
Q

TNF alpha can activate

A

Caspase

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14
Q

Measles mannifestation

A

rubeola
conjunctivitis
cough
coryza

RASH –maculopapular starts at head SPARES HANDS AND SOLES —- spreads down

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15
Q

rash taht includes palms soles

A
CARS
Coxsackie
A
Rickestia ricketsie
Syphilus
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16
Q

Sub acute sclerosing panecephalitis

A

myoclonus
caused by mutated or absent measles matrix protein —- prevents mature enveloped virion particle formation—- virus continously replicates

intranuclear inclusions in the oligodendrocytes
increased measles antibodies oligoclonal bands
dementia

17
Q

what other conditions present wtih myoclonus

A

myoclonic epilepsy
SSPE
prion disease
opsoclonus myoclonus synd (neuroblastoma in children and SCLC in adults)

18
Q

what type of lymphocytes are seen in encephalitis caused by measles

A

warthin finkeldey Giant cells — fused aggregated lymphocytes
immunocomp —- increased giant cell pneumonia

19
Q

prophylaxis of measles

A

vit A

acute infection uses up vitamin A stores —- risk of keratitis and corneal ulceration

20
Q

mumps (paramyxo)

A
POMPS
parotitis
orchitis---- sterility
meningitis----- aseptic meningitis
pancreatitis
21
Q

RF of suppurative parotitis

A

obstruction —- calculus stone or tumors

sialolithiasis — stone in salivary duct

22
Q

Parotid/ submandibular / sublingual nerves

23
Q

nerves that have parasymp functionn

24
Q

submandibular duct mostly has — stones

A

single stone —wharton duct

PAIN — pre post prandial

25
R/F for silolithiasis
dehydration diurects trauma
26
treatment for silolithiasis
warm compressions NSAIDS massage sour candies
27
salivary gland tumors involves which salivary gland
PAROTID ---- benign mostly swelling and painless painful wen involve facial nerve ( malignant)
28
less common tumors
sub mandibular and sublingual ---- malignant
29
most common benign salivary gland tumor 1
PLEOMORPHIC ADENOMA mixed tumor stromal tissue - cartilage ( chondromyxoid) epithelial tissue angle of jaw reover despite ressection --- extend to capsule
30
most common benign SGT 2
warthin tumor psammoma bodies --- papilary cystadenoma lymphomatosum benign cystic tumor with lymphocytes germinal centers can be bilateral too in 10%
31
smokers at risk for which salivary gland tumor
warthin
32
malignant SGT
mucoepidermal carcinoma mucinous /squamous involves facial nerve
33
other causes of suppurative parotitis
anticholinergic meds intubation post surgery sjogern
34
pathogen for parotitis
staph a | anaerobes
35
choice of investigation parotitis
US/CT aspiration increased AMYLASE
36
Reo virus
12 segments Ds RNA virus colti --- colarado tick rota
37
rota virus infects what
enterocytes villi of duodenum and prox jejunum ---- BLUNTING OF VILLI secretary crypt cells start prolif --- na/k lost brush border enzyme lost --- disaccharide test
38
diarrhea in rota virus
non inflammatory | no leukocytes no RBCs
39
when to avoid rota virus vaccine
intussusception | SCID pts