cvs 18 Flashcards

1
Q

bithermal antibidy

A

IgG

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2
Q

mycoplasma and mononucleosis have these antibodies

A

IgM

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3
Q

which drugs can cause AIHA with IgG DONETH LANDSTEIN ab

A

pennicillin
2/3 penicillin
methyldopa
quinidine

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4
Q

antibodies against GP IIb IIIA

A

ITP

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5
Q

decrease exp of GP IIB IIIA

A

glanzman thrombocytopenia

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6
Q

direct combs test

A

antibody + RBC

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7
Q

indirect comb

A

normal RBC mix with serum of pt (AB)

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8
Q

RSV is most common cause of

A

bronchiolitis in babies

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9
Q

mannifestation and RF of bronchiolitis

A

nasal cong/distress/ flaring
tachypnea
wheezes/ crackles
RF——- prematurity —- resp failure

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10
Q

prophylaxiis for RSV

A

palivizumab —- fusion protein inhibtor

ribavirin (CHAIR mnemonic)

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11
Q

CLL mnemonic

A
HATS
Hypogammaglobulinemia
AIHA
Transf to DLBL
Small lymphocytic lymph

SMUDGE CELLS —- CD5 CD20

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12
Q

mechanism of Denosumab

A

mimics osteoprotegrin !! — acivates clast

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13
Q

TNF alpha can activate

A

Caspase

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14
Q

Measles mannifestation

A

rubeola
conjunctivitis
cough
coryza

RASH –maculopapular starts at head SPARES HANDS AND SOLES —- spreads down

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15
Q

rash taht includes palms soles

A
CARS
Coxsackie
A
Rickestia ricketsie
Syphilus
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16
Q

Sub acute sclerosing panecephalitis

A

myoclonus
caused by mutated or absent measles matrix protein —- prevents mature enveloped virion particle formation—- virus continously replicates

intranuclear inclusions in the oligodendrocytes
increased measles antibodies oligoclonal bands
dementia

17
Q

what other conditions present wtih myoclonus

A

myoclonic epilepsy
SSPE
prion disease
opsoclonus myoclonus synd (neuroblastoma in children and SCLC in adults)

18
Q

what type of lymphocytes are seen in encephalitis caused by measles

A

warthin finkeldey Giant cells — fused aggregated lymphocytes
immunocomp —- increased giant cell pneumonia

19
Q

prophylaxis of measles

A

vit A

acute infection uses up vitamin A stores —- risk of keratitis and corneal ulceration

20
Q

mumps (paramyxo)

A
POMPS
parotitis
orchitis---- sterility
meningitis----- aseptic meningitis
pancreatitis
21
Q

RF of suppurative parotitis

A

obstruction —- calculus stone or tumors

sialolithiasis — stone in salivary duct

22
Q

Parotid/ submandibular / sublingual nerves

A

977

23
Q

nerves that have parasymp functionn

A

3 7 9 10

24
Q

submandibular duct mostly has — stones

A

single stone —wharton duct

PAIN — pre post prandial

25
Q

R/F for silolithiasis

A

dehydration
diurects
trauma

26
Q

treatment for silolithiasis

A

warm compressions
NSAIDS
massage
sour candies

27
Q

salivary gland tumors involves which salivary gland

A

PAROTID —- benign mostly

swelling and painless
painful wen involve facial nerve ( malignant)

28
Q

less common tumors

A

sub mandibular and sublingual —- malignant

29
Q

most common benign salivary gland tumor 1

A

PLEOMORPHIC ADENOMA
mixed tumor
stromal tissue - cartilage ( chondromyxoid)
epithelial tissue
angle of jaw
reover despite ressection — extend to capsule

30
Q

most common benign SGT 2

A

warthin tumor
psammoma bodies — papilary cystadenoma lymphomatosum

benign cystic tumor with lymphocytes
germinal centers
can be bilateral too in 10%

31
Q

smokers at risk for which salivary gland tumor

A

warthin

32
Q

malignant SGT

A

mucoepidermal carcinoma
mucinous /squamous

involves facial nerve

33
Q

other causes of suppurative parotitis

A

anticholinergic meds
intubation
post surgery
sjogern

34
Q

pathogen for parotitis

A

staph a

anaerobes

35
Q

choice of investigation parotitis

A

US/CT
aspiration

increased AMYLASE

36
Q

Reo virus

A

12 segments Ds RNA virus

colti — colarado tick
rota

37
Q

rota virus infects what

A

enterocytes villi of duodenum and prox jejunum —- BLUNTING OF VILLI

secretary crypt cells start prolif — na/k lost

brush border enzyme lost — disaccharide test

38
Q

diarrhea in rota virus

A

non inflammatory

no leukocytes no RBCs

39
Q

when to avoid rota virus vaccine

A

intussusception

SCID pts