DERM - Introduction to dermatology Flashcards Preview

Year 2 Specialty Medicine > DERM - Introduction to dermatology > Flashcards

Flashcards in DERM - Introduction to dermatology Deck (31):
1

what is the atopic triad?

- asthma
- allergies
- atopic dermatitis

2

what are the flat lesions? how are they differentiated?

- macule: under 1 cm
- patch: over 1 cm

3

what are the raised, solid lesions? how are they differentiated?

- papule: under 1 cm
- nodule: over 1 cm
- tumor: over 2 cm
- plaque: over 1 cm FLAT topped ("plateau")

4

what are the raised fluild filled lesions? how are the differentiated?

- vesicles: clear fluid, under 1 cm
- bulla: clear fluid, over 1 cm
- pustule: white fluid, filled with pus

5

are telangiectasias blanchable or non-blanchable?

blanchable

6

definition: erosion

loss of epidermis, depression in skin, heals WITHOUT scar

7

definition: scale

flake or plates of skin

8

what is used to visualize tinea versicolor?

woods light

9

spaghetti and meatballs appearance on woods light - diagnosis?

tinea versicolor

10

what is the organism responsible for tinea versicolor?

malassezia furfur

11

malassezia furfur is responsible for what condition?

tinea versicolor

12

what is the treatment for tinea versicolor?

ketoconazole shampoo, topical antifungals

13

what is the mechanism of action of topical steroids?

- inhibition of NF-kB, suppressing both B and TC function
- no cytokine transcription

14

are imidazoles fungistatic or fungicidal?

fungistatic (azoles!)

15

are allylamines fungistatic or fungicidal?

fungicidal

16

are polyenes fungistatic or fungicidal?

fungicidal

17

are allylamines better for dermatophytes or candida?

dermatophytes

18

are polyenes better for dermatophytes or candida?

candida

19

what is the MOA of the imidazoles?

- inhibit 14-a-demethylase
- stops lanosterol from forming ergosterol
- p450 enzyme inhibitors****

20

what are the side effects of the imidazoles?

- antiandrogen
- liver toxicity
- drug interactions

21

what is the MOA of the allylamines?

inhibit squalene epoxidase

22

what are the side effects of the allylamines and polyenes?

- taste deficiency
- liver toxicity
- HA
- GI

23

what are the first generation antihistamines?

- diphenhydramine
- hydroxyzine
- chlorpheniramine

24

what are the second generation antihistamines?

- cetirizine
- loratidine
- fexofenadine (best for itch)

25

which antihistamine is best for itch?

fexofenadine

26

what is ranitidine used for? what is the MOA?

- GERD
- H2 blocker

27

what is the target for psoriasis medication?

inhibition of keratinocyte proliferation

28

what are the psoriasis meds?

- coal tar
- tazarotene
- vitamin D analogs

29

what are the most specific antibodies for lupus?

- anti dsDNA
- anti smith

30

what are the common causes of death in lupus patients?

1. CV
2. infection
3. renal disease

31

which drugs can cause SLE?

- sulfa
- hydralazine
- INH
- procainamide
- phenytoin
- etanercept